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ITCH/AIP4 Antibody (01) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
01
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-06616AF350
Alexa Fluor 405
NBP3-06616AF405
Alexa Fluor 488
NBP3-06616AF488
Alexa Fluor 532
NBP3-06616AF532
Alexa Fluor 594
NBP3-06616AF594
Alexa Fluor 647
NBP3-06616AF647
Alexa Fluor 700
NBP3-06616AF700
Alexa Fluor 750
NBP3-06616AF750
Allophycocyanin
NBP3-06616APC
Biotin
NBP3-06616B
CoraFluor 1
NBP3-06616CL1
DyLight 350
NBP3-06616UV
DyLight 405
NBP3-06616V
DyLight 488
NBP3-06616G
DyLight 550
NBP3-06616R
DyLight 594
NBP3-06616DL594
DyLight 650
NBP3-06616C
DyLight 680
NBP3-06616FR
DyLight 755
NBP3-06616IR
HRP
NBP3-06616H
Janelia Fluor 525
NBP3-06616JF525
Janelia Fluor 549
NBP3-06616JF549
Janelia Fluor 585
NBP3-06616JF585
Janelia Fluor 635
NBP3-06616JF635
Janelia Fluor 646
NBP3-06616JF646
Janelia Fluor 669
NBP3-06616JF669
PE
NBP3-06616PE
PerCP
NBP3-06616PCP
Unconjugated
NBP3-06616-100ul
mFluor Violet 450 SE
NBP3-06616MFV450
mFluor Violet 500 SE
NBP3-06616MFV500
mFluor Violet 610 SE
NBP3-06616MFV610
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ITCH/AIP4 Antibody (01) [FITC] Summary

Immunogen
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ITCH/AIP4 (Accession#: NP_113671.3; Arg526-Glu903).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITCH
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for ITCH/AIP4 Antibody (01) [FITC]

  • AIF4
  • AIP4
  • AIP4dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4))
  • atrophin-1 interacting protein 4
  • Atrophin-1-interacting protein 4
  • dJ468O1.1
  • EC 6.3.2
  • EC 6.3.2.-
  • ITCH
  • itchy (mouse homolog) E3 ubiquitin protein ligase
  • itchy E3 ubiquitin protein ligase homolog (mouse)
  • itchy homolog E3 ubiquitin protein ligase
  • NAPP1
  • NAPP1E3 ubiquitin-protein ligase Itchy homolog
  • NFE2-associated polypeptide 1
  • ubiquitin protein ligase ITCH

Background

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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ITCH/AIP4 Antibody
(01) [FITC]
NBP3-06616F
ITCH/AIP4 Antibody (01) [FITC]
Species: Hu
Applications: Flow, ICC/IF

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Bioinformatics

Gene Symbol ITCH