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ISCU Antibody (OTI4F5) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI4F5
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71742AF350
Alexa Fluor 405
NBP2-71742AF405
Alexa Fluor 488
NBP2-71742AF488
Alexa Fluor 532
NBP2-71742AF532
Alexa Fluor 594
NBP2-71742AF594
Alexa Fluor 647
NBP2-71742AF647
Alexa Fluor 700
NBP2-71742AF700
Alexa Fluor 750
NBP2-71742AF750
Allophycocyanin
NBP2-71742APC
Biotin
NBP2-71742B
CoraFluor 1
NBP2-71742CL1
DyLight 405
NBP2-71742V
DyLight 488
NBP2-71742G
DyLight 550
NBP2-71742R
DyLight 594
NBP2-71742DL594
DyLight 650
NBP2-71742C
DyLight 680
NBP2-71742FR
DyLight 755
NBP2-71742IR
FITC
NBP2-71742F
HRP
NBP2-71742H
Janelia Fluor 525
NBP2-71742JF525
Janelia Fluor 549
NBP2-71742JF549
Janelia Fluor 585
NBP2-71742JF585
Janelia Fluor 635
NBP2-71742JF635
Janelia Fluor 646
NBP2-71742JF646
Janelia Fluor 669
NBP2-71742JF669
PE
NBP2-71742PE
PerCP
NBP2-71742PCP
Unconjugated
NBP2-45436
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45436
Azide and BSA Free
NBP2-71742
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ISCU Antibody (OTI4F5) [DyLight 350] Summary

Immunogen
Full length recombinant protein of human ISCU (NP_055116) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ISCU
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ISCU Antibody (OTI4F5) [DyLight 350]

  • 2310020H20Rik
  • HML
  • hnifU
  • iron-sulfur cluster assembly enzyme ISCU, mitochondrial
  • iron-sulfur cluster scaffold homolog (E. coli)
  • IscU iron-sulfur cluster scaffold homolog (E. coli)
  • IscU iron-sulfur cluster scaffold homolog
  • IscU
  • ISU2
  • MGC74517
  • NIFU
  • NifU-like N-terminal domain containing
  • NifU-like N-terminal domain-containing protein
  • NifU-like protein
  • NIFUN

Background

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ISCU