ISCU Products

Description

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Bioinformatics

Entrez	23479 Human
Uniprot	AAH11906 Human NM_213595 Human NP_055116 Human NP_998760 Human Q9H1K1 Human
Product By Gene ID	23479
Alternate Names	2310020H20Rik HML hnifU iron-sulfur cluster assembly enzyme ISCU, mitochondrial iron-sulfur cluster scaffold homolog (E. coli) IscU iron-sulfur cluster scaffold homolog (E. coli) IscU iron-sulfur cluster scaffold homolog IscU ISU2 MGC74517 NIFU NifU-like N-terminal domain containing NifU-like N-terminal domain-containing protein NifU-like protein NIFUN