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Integrin alpha 5/CD49e Antibody (238307) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, Func, ICC/IF
Clone
238307
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1864U-100UG
Alexa Fluor 405
FAB1864V-100UG
Alexa Fluor 488
FAB1864G-100UG
Alexa Fluor 532
FAB1864X
Alexa Fluor 594
FAB1864T-100UG
Alexa Fluor 647
FAB1864R-100UG
Alexa Fluor 700
FAB1864N-100UG
Alexa Fluor 750
FAB1864S-100UG
Allophycocyanin
FAB1864A
Allophycocyanin/Cy7
FAB1864APCCY7
Biotin
FAB1864B
CoraFluor 1
FAB1864CL1
DyLight 350
FAB1864D
DyLight 405
FAB1864E
DyLight 488
FAB1864K
DyLight 550
FAB1864L
DyLight 650
FAB1864W
DyLight 680
FAB1864Y
DyLight 755
FAB1864Z
FITC
FAB1864F
HRP
FAB1864H
Janelia Fluor 525
FAB1864JF525
Janelia Fluor 549
FAB1864I
Janelia Fluor 646
FAB1864J
Janelia Fluor 669
FAB1864JF669
PE/Atto594
FAB1864PEATT594
PE/Cy5.5
FAB1864PECY55
PE/Cy7
FAB1864PECY7
PerCP
FAB1864C
Phycoerythrin
FAB1864P
Unconjugated
MAB1864
mFluor Violet 450 SE
FAB1864MFV450
mFluor Violet 500 SE
FAB1864MFV500
mFluor Violet 610 SE
FAB1864MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB1864
Carrier Free
FAB1864A
Carrier Free
FAB1864P
Carrier Free
MAB1864
Carrier Free
MAB1864-SP
Carrier Free
FAB1864V-100UG
Carrier Free
FAB1864U-100UG
Carrier Free
FAB1864T-100UG
Carrier Free
FAB1864S-100UG
Carrier Free
FAB1864R-100UG
Carrier Free
FAB1864N-100UG
Carrier Free
FAB1864G-100UG
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Integrin alpha 5/CD49e Antibody (238307) [DyLight 594] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Integrin alpha 5/CD49e
Phe42-Tyr995
Accession # P08648
Specificity
Detects human Integrin alpha 5/CD49e.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGA5
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Adhesion Activation
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Integrin alpha 5/CD49e Antibody (238307) [DyLight 594]

  • CD49 antigen-like family member E
  • CD49e antigen
  • CD49e
  • Fibronectin receptor subunit alpha
  • fibronectin receptor, alpha subunit
  • FNRAVLA5A
  • Integrin alpha 5
  • integrin alpha-5
  • Integrin alpha-F
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
  • ITGA5
  • very late activation protein 5, alpha subunit
  • VLA-5 alpha
  • VLA-5

Background

CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGA5