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IL-6 Antibody (OTI3G9) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI3G9
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71027AF350
Alexa Fluor 405
NBP2-71027AF405
Alexa Fluor 488
NBP2-71027AF488
Alexa Fluor 532
NBP2-71027AF532
Alexa Fluor 594
NBP2-71027AF594
Alexa Fluor 647
NBP2-71027AF647
Alexa Fluor 700
NBP2-71027AF700
Alexa Fluor 750
NBP2-71027AF750
Allophycocyanin
NBP2-71027APC
Biotin
NBP2-71027B
CoraFluor 1
NBP2-71027CL1
DyLight 350
NBP2-71027UV
DyLight 405
NBP2-71027V
DyLight 488
NBP2-71027G
DyLight 550
NBP2-71027R
DyLight 594
NBP2-71027DL594
DyLight 650
NBP2-71027C
DyLight 680
NBP2-71027FR
DyLight 755
NBP2-71027IR
FITC
NBP2-71027F
HRP
NBP2-71027H
Janelia Fluor 549
NBP2-71027JF549
Janelia Fluor 646
NBP2-71027JF646
Janelia Fluor 669
NBP2-71027JF669
PE
NBP2-71027PE
PerCP
NBP2-71027PCP
Unconjugated
NBP1-47810
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-47810
Azide and BSA Free
NBP2-71027
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IL-6 Antibody (OTI3G9) [Janelia Fluor® 525] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 29-212 of human IL-6 (NP_000591) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IL6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL-6 Antibody (OTI3G9) [Janelia Fluor® 525]

  • B-cell differentiation factor
  • B-cell stimulatory factor 2
  • BSF2
  • BSF-2
  • CDF
  • CTL differentiation factor
  • HSF
  • hybridoma growth factor
  • IFNB2
  • IFN-beta-2
  • IL6
  • IL-6
  • Interferon beta-2
  • interleukin 6 (interferon, beta 2)
  • interleukin BSF-2
  • interleukin-6
  • MGI-2A

Background

IL-6 is a multifunctional cytokine that has an important role in host defense by regulating immune and inflammatory responses. It is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts and various tumor cells. IL-6 has diverse biological functions, it stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Human IL-6 is active on murine cells but murine IL-6 is inactive on human cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-71027JF525
IL-6 Antibody (OTI3G9) [Janelia Fluor® 525]
Species: Hu
Applications: WB, ICC/IF, IHC

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IL-6 Antibody (NBP2-71027JF525). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL6