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IL-6 Antibody (1936) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, B/N, CyTOF-ready, Flow, ICC/IF
Clone
1936
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC2061U-100UG
Alexa Fluor 405
IC2061V-100UG
Alexa Fluor 488
IC2061G-100UG
Alexa Fluor 532
FAB2061X
Alexa Fluor 594
IC2061T-100UG
Alexa Fluor 647
IC2061R-100UG
Alexa Fluor 700
IC2061N-100UG
Alexa Fluor 750
IC2061S-100UG
Allophycocyanin
FAB2061A
Biotin
FAB2061B
DyLight 350
FAB2061D
DyLight 405
FAB2061E
DyLight 488
FAB2061K
DyLight 550
FAB2061L
DyLight 594
FAB2061M
DyLight 650
FAB2061W
DyLight 680
FAB2061Y
DyLight 755
FAB2061Z
Fluorescein
IC206F
HRP
FAB2061H
Janelia Fluor 525
FAB2061JF525
Janelia Fluor 549
FAB2061I
Janelia Fluor 646
FAB2061J
Janelia Fluor 669
FAB2061JF669
PerCP
FAB2061C
Phycoerythrin
IC206P
Unconjugated
MAB2061-100
mFluor Violet 450 SE
FAB2061MFV450
mFluor Violet 500 SE
FAB2061MFV500
mFluor Violet 610 SE
FAB2061MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2061-100
Carrier Free
IC206F
Carrier Free
IC206P
Carrier Free
MAB2061-SP
Carrier Free
MAB2061-100
Carrier Free
MAB2061-500
Carrier Free
IC2061V-100UG
Carrier Free
IC2061U-100UG
Carrier Free
IC2061T-100UG
Carrier Free
IC2061S-100UG
Carrier Free
IC2061R-100UG
Carrier Free
IC2061N-100UG
Carrier Free
IC2061G-100UG
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IL-6 Antibody (1936) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
E. coli-derived recombinant human IL‑6
Val30-Met212
Accession # P05231
Specificity
Detects human IL-6 in direct ELISAs. Does not cross-react with recombinant IL-6 from mouse, rat, or pig.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
IL6
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for IL-6 Antibody (1936) [CoraFluor™ 1]

  • B-cell differentiation factor
  • B-cell stimulatory factor 2
  • BSF2
  • BSF-2
  • CDF
  • CTL differentiation factor
  • HSF
  • hybridoma growth factor
  • IFNB2
  • IFN-beta-2
  • IL6
  • IL-6
  • Interferon beta-2
  • interleukin 6 (interferon, beta 2)
  • interleukin BSF-2
  • interleukin-6
  • MGI-2A

Background

IL-6 is a multifunctional cytokine that has an important role in host defense by regulating immune and inflammatory responses. It is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts and various tumor cells. IL-6 has diverse biological functions, it stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Human IL-6 is active on murine cells but murine IL-6 is inactive on human cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAB2061CL1
IL-6 Antibody (1936) [CoraFluor™ 1]
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FAQs for IL-6 Antibody (FAB2061CL1). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

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Bioinformatics

Gene Symbol IL6