IL-24 Antibody (C7) Summary
Immunogen |
Immunized with recombinant Rat IL-24 (Uniprot#: Q9JI24; Gln29-Leu183 (Uniprot#: Q9JI24) |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
IL24 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 5-20ug/mL
- Immunohistochemistry 5-20ug/mL
- Western Blot 0.5-2ug/mL
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
0.01M PBS, pH7.4, 50% glycerol |
Preservative |
0.05% Proclin 300 |
Concentration |
1 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for IL-24 Antibody (C7)
Background
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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