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IL-24 Antibody (C7)

Images

 
Immunohistochemistry-Paraffin: IL-24 Antibody (C7) [NBP3-42153] - DAB staining on IHC-P; Sample: Rat Stomach Tissue; Primary Ab: 30ug/ml NBP3-42153; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal ...read more
Immunohistochemistry-Paraffin: IL-24 Antibody (C7) [NBP3-42153] - DAB staining on IHC-P; Sample: Rat Skin Tissue; Primary Ab: 30ug/ml NBP3-42153; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Immunohistochemistry-Paraffin: IL-24 Antibody (C7) [NBP3-42153] - DAB staining on IHC-P; Sample: Rat Small intestine Tissue; Primary Ab: 30ug/ml NBP3-42153; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
C7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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IL-24 Antibody (C7) Summary

Immunogen
Immunized with recombinant Rat IL-24 (Uniprot#: Q9JI24; Gln29-Leu183 (Uniprot#: Q9JI24)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IL24
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for IL-24 Antibody (C7)

  • C49A
  • FISP
  • IL10B
  • IL24
  • IL-24
  • interleukin 24
  • MDA-7
  • MDA7MOB5
  • melanocyte-associated Mda-7
  • melanoma differentiation association protein 7
  • Melanoma differentiation-associated gene 7 protein
  • MOB-5
  • ST16
  • ST16interleukin-24
  • suppression of tumorigenicity 16 (melanoma differentiation)
  • Suppression of tumorigenicity 16 protein

Background

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL24