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IL-17RB Antibody - BSA Free

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Orthogonal Strategies: Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Analysis in human kidney and skeletal muscle tissues using NBP1-85450 antibody. Corresponding IL17RB RNA-seq data are ...read more
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human liver shows strong cytoplasmic and membranous positivity in hepatocytes.
Immunohistochemistry-Paraffin: IL-17RB Antibody [NBP1-85450] - Staining of human lymphoid tissues shows no positivity in non-germinal center cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Validated by:
       

Orthogonal Strategies

 

Order Details

IL-17RB Antibody - BSA Free Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: QCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IL17RB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
IL-17RB Recombinant Protein Antigen (NBP1-85450PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for IL-17RB Antibody - BSA Free

  • CRL4IL-17 receptor homolog 1
  • cytokine receptor CRL4
  • Cytokine receptor-like 4
  • Evi27
  • EVI27IL-17B receptor
  • IL-17 RB
  • IL-17 receptor B
  • IL-17 RH1
  • IL17BRinterleukin 17B receptor
  • IL-17ER
  • IL17RB
  • IL-17RB
  • IL17Rh1
  • IL-17Rh1
  • IL17RH1MGC5245
  • interleukin 17 receptor B
  • interleukin 17 receptor homolog 1
  • interleukin-17 receptor B
  • Interleukin-17B receptor

Background

IL17B Receptor is encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL17RB