Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Tyro3/Dtk DuoSet ELISA, 15 Plate
Brt
BYK
Dtk
EC 2.7.10
EC 2.7.10.1
FLJ16467
Rse
Sky
Tif
TYRO3 protein tyrosine kinase
Tyro3
Tyrosine-protein kinase byk
Tyrosine-protein kinase DTK
tyrosine-protein kinase receptor TYRO3
Tyrosine-protein kinase RSE
Tyrosine-protein kinase SKY
Background
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse orthologs of chicken c-Eyk) constitute the TAM receptor tyrosine kinase subfamily. This RTK subfamily is characterized by an extracellular domain that consists of two Ig-like motifs and two fibronectin type III motifs. These receptors bind the vitamin K-dependent protein Growth Arrest Specific Gene 6 (Gas6). Receptor activation leads to cell proliferation, migration, or the prevention of apoptosis. Cellular signaling through this family of RTKs is involved in hematopoiesis, embryonic development, tumorigenesis, and spermatogenesis.