Human Phospho-VEGFR1/Flt-1 DuoSet IC ELISA, 2 Plate Summary
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
Intra-Assay
Spike Recovery
Sample Volume
Gene
FLT1
Applications/Dilutions
Dilutions
Application Notes
No significant interference observed with available related molecules.
Publications
Packaging, Storage & Formulations
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Phospho-VEGFR1/Flt-1 DuoSet IC ELISA, 2 Plate
Background
VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.
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Publications for VEGFR1/Flt-1 (DYC4170-2)(4)
We have publications tested in 2 confirmed species: Human, Bovine.
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Showing Publications 1 -
4 of 4.
Publications using DYC4170-2
Applications
Species
T Yao, H Chen, R Wang, R Rivero, F Wang, L Kessels, SM Agten, TM Hackeng, TGAM Wolfs, D Fan, MB Baker, L Moroni Thiol-ene conjugation of VEGF peptide to electrospun scaffolds as potential application for angiogenesis Bioactive materials, 2022-06-08;20(0):306-317. 2022-06-08 [PMID: 35755423] (Human)
Human
JAF Silva, X Qi, MB Grant, ME Boulton Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells Scientific Reports, 2021-08-30;11(1):17400. 2021-08-30 [PMID: 34462507] (Human)
Human
M Su, B Qin, F Liu, Y Chen, R Zhang Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway Drug Des Devel Ther, 2017-11-23;11(0):3333-3341. 2017-11-23 [PMID: 29200829] (Human)
Human
Cai J, Chen Z, Ruan Q, Han S, Liu L, Qi X, Boye SL, Hauswirth WW, Grant MB, Boulton ME gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. J. Biol. Chem., 2011-10-20;286(49):42514-23. 2011-10-20 [PMID: 22016384] (Bovine)
Bovine
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