Human PDGF-AB DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 8 of 8.

Publications using DY222	Applications	Species
Delila, L;Nebie, O;Le, NTN;Timmerman, K;Lee, DY;Wu, YW;Chou, ML;Buée, L;Chou, SY;Blum, D;Devos, D;Burnouf, T; Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease models Journal of biomedical science 2024-09-05 [PMID: 39237980] (Human)		Human
Lengvenyte, A;Cognasse, F;Hamzeh-Cognasse, H;Sénèque, M;Strumila, R;Olié, E;Courtet, P; Baseline circulating biomarkers, their changes, and subsequent suicidal ideation and depression severity at 6 months: A prospective analysis in patients with mood disorders Psychoneuroendocrinology 2024-07-06 [PMID: 39003840] (Human)		Human
A Jarosz, K Szyluk, J Iwanicka, A Balcerzyk, T Nowak, T Iwanicki, M Negru, M Kalita, T Francuz, W Garczorz, S Górczy?ska, W Kania, P Niemiec What Role Does PDGFA Gene Polymorphisms Play in Treating Tennis Elbow with PRP? A Prospective Cohort Study Oncogene, 2022-06-17;11(12):. 2022-06-17 [PMID: 35743573] (Human)		Human
P Niemiec, K Szyluk, A Balcerzyk, M Kalita, A Jarosz, J Iwanicka, T Iwanicki, T Nowak, M Negru, T Francuz, W Garczorz, W Grzeszczak, S Górczy?ska, W Kania, I ?ak Why PRP works only on certain patients with tennis elbow? Is PDGFB gene a key for PRP therapy effectiveness? A prospective cohort study Bmc Musculoskeletal Disorders, 2021-08-18;22(1):710. 2021-08-18 [PMID: 34407802] (Human)		Human
O Nebie, D Devos, V Vingtdeux, L Barro, JC Devedjian, A Jonneaux, ML Chou, R Bordet, L Buée, F Knutson, D Blum, T Burnouf The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates J. Biomed. Sci., 2019-10-31;26(1):89. 2019-10-31 [PMID: 31666073] (Human)		Human
A Islam, I Urbarova, JA Bruun, I Martinez-Z Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells Eur Cell Mater, 2019-02-20;37(0):153-174. 2019-02-20 [PMID: 30785213] (Human)		Human
MS Chen, TJ Wang, HC Lin, B Thierry Four types of human platelet lysate, including one virally inactivated by solvent-detergent, can be used to propagate Wharton Jelly mesenchymal stromal cells New biotechnology, 2018-11-20;0(0):. 2018-11-20 [PMID: 30465908] (Human)		Human
Boneberg EM, Legler DF, Hoefer MM, Ohlschlegel C, Steininger H, Fuzesi L, Beer GM, Dupont-Lampert V, Otto F, Senn HJ, Furstenberger G Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. Br. J. Cancer, 2009-08-18;101(4):605-14. 2009-08-18 [PMID: 19672262] (Human)		Human

Array DY222

• PDGF-AB ELISA Kit
• PDGF-AB ELISAs
• PDGF-AB Proteins and Enzymes