Human FABP2/I-FABP Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Fatty acid binding proteins are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner. FABPs bind free fatty acids, cholesterol, and retinoids, and are involved in intracellular lipid transport. Circulating FABP levels are used as indicators of tissue damage. Some FABP polymorphisms have been associated with disorders of lipid metabolism and the development of atherosclerosis.

FABP2, also known as intestinal fatty acid binding protein (I-FABP or FABPI) and gut FABP (gFABP), is a member of the cytosolic fatty acid binding protein family. FABP2 mediates the absorption and intracellular transport of dietary long-chain fatty acids. Genetic variations of FABP2 are implicated in obesity and Type II diabetes. Human FABP2 shares 78%, 82%, and 86% amino acid sequence identity with mouse, rat, and canine FABP2, respectively.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 28. Show All 28 Publications. Collapse Publications.

Publications using DFBP20	Applications	Species
Miuma, S;Miyaaki, H;Taura, N;Kanda, Y;Matsuo, S;Tajima, K;Takahashi, K;Nakao, Y;Fukushima, M;Haraguchi, M;Sasaki, R;Ozawa, E;Ichikawa, T;Nakao, K; Elevated intestinal fatty acid-binding protein levels as a marker of portal hypertension and gastroesophageal varices in cirrhosis Scientific reports 2024-10-23 [PMID: 39443545] (Human)		Human
Tamme, K;Acosta, S;Biloslavo, A;Björck, M;Casian, D;Damaskos, D;Forbes, A;Kase, K;Kisand, K;Lakbar, I;Mihnovitš, V;Murruste, M;Mändul, M;Nuzzo, A;Padar, M;Starkopf, J;Visconti, D;Reintam Blaser, A; Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol BMC surgery 2024-07-03 [PMID: 38961419] (Human)		Human
Liu, Q;Wang, Z;Sun, S;Nemes, J;Brenner, LA;Hoisington, A;Skotak, M;LaValle, CR;Ge, Y;Carr, W;Haghighi, F; Association of Blast Exposure in Military Breaching with Intestinal Permeability Blood Biomarkers Associated with Leaky Gut International journal of molecular sciences 2024-03-21 [PMID: 38542520] (Human)		Human
Rocafort, M;Gootenberg, DB;Luévano, JM;Paer, JM;Hayward, MR;Bramante, JT;Ghebremichael, MS;Xu, J;Rogers, ZH;Munoz, AR;Okello, S;Kim, JH;Sentongo, R;Wagubi, R;Lankowski, A;Maruapula, S;Zhao, G;Handley, SA;Mosepele, M;Siedner, MJ;Kwon, DS; HIV-associated gut microbial alterations are dependent on host and geographic context Nature communications 2024-02-05 [PMID: 38316748] (Human)		Human
Huang, Y;Zhang, L;Karuna, S;Andrew, P;Juraska, M;Weiner, JA;Angier, H;Morgan, E;Azzam, Y;Swann, E;Edupuganti, S;Mgodi, NM;Ackerman, ME;Donnell, D;Gama, L;Anderson, PL;Koup, RA;Hural, J;Cohen, MS;Corey, L;McElrath, MJ;Gilbert, PB;Lemos, MP; Adults on pre-exposure prophylaxis (tenofovir-emtricitabine) have faster clearance of anti-HIV monoclonal antibody VRC01 Nature communications 2023-11-28 [PMID: 38016958] (Human)		Human
Zhang, FL;Hu, Z;Wang, YF;Zhang, WJ;Zhou, BW;Sun, QS;Lin, ZB;Liu, KX; Organoids transplantation attenuates intestinal ischemia/reperfusion injury in mice through L-Malic acid-mediated M2 macrophage polarization Nature communications 2023-10-25 [PMID: 37880227] (Human)		Human
Chen, Y;Han, B;Guan, X;Du, G;Sheng, B;Tang, X;Zhang, Q;Xie, H;Jiang, X;Tan, Q;Chen, S;Wang, J;Chen, W;Xiao, W; Enteric fungi protect against intestinal ischemia-reperfusion injury via inhibiting the SAA1-GSDMD pathway Journal of advanced research 2023-09-15 [PMID: 37717911] (Mouse)		Mouse
Zhang, W;Zhou, B;Yang, X;Zhao, J;Hu, J;Ding, Y;Zhan, S;Yang, Y;Chen, J;Zhang, F;Zhao, B;Deng, F;Lin, Z;Sun, Q;Zhang, F;Yao, Z;Liu, W;Li, C;Liu, KX; Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling Nature communications 2023-09-06 [PMID: 37673874] (Human)		Human
Tyszko, M;Lemańska-Perek, A;Śmiechowicz, J;Tomaszewska, P;Biecek, P;Gozdzik, W;Adamik, B; Citrulline, Intestinal Fatty Acid-Binding Protein and the Acute Gastrointestinal Injury Score as Predictors of Gastrointestinal Failure in Patients with Sepsis and Septic Shock Nutrients 2023-04-27 [PMID: 37432225] (Human)		Human
A Stec, M Maciejewsk, M Zaremba, K Paralusz-S, M Michalska, L Rudnicka, M Sikora The Clinical Significance of Serum Biomarkers of the Intestinal Barrier in Systemic Sclerosis: A Cross-Sectional Study Journal of personalized medicine, 2023-04-18;13(4):. 2023-04-18 [PMID: 37109064] (Human)		Human
FL Zhang, XW Chen, YF Wang, Z Hu, WJ Zhang, BW Zhou, PF Ci, KX Liu Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2 Journal of Translational Medicine, 2023-04-18;21(1):264. 2023-04-18 [PMID: 37072757] (Human)		Human
J Choi, JH Kim, M Park, HJ Lee Effects of Flavonoid-Rich Orange Juice Intervention on Major Depressive Disorder in Young Adults: A Randomized Controlled Trial Nutrients, 2022-12-28;15(1):. 2022-12-28 [PMID: 36615801] (Human)		Human
G Assante, A Tourna, R Carpani, F Ferrari, D Prati, F Peyvandi, F Blasi, A Bandera, A Le Guennec, S Chokshi, VC Patel, IJ Cox, L Valenti, NA Youngson Reduced circulating FABP2 in patients with moderate to severe COVID-19 may indicate enterocyte functional change rather than cell death Scientific Reports, 2022-11-05;12(1):18792. 2022-11-05 [PMID: 36335131] (Human)		Human
H Deng, L He, C Wang, T Zhang, H Guo, H Zhang, Y Song, B Chen Altered gut microbiota and its metabolites correlate with plasma cytokines in schizophrenia inpatients with aggression BMC Psychiatry, 2022-09-27;22(1):629. 2022-09-27 [PMID: 36167540] (Human)		Human
R Prasad, MJ Patton, JL Floyd, S Fortmann, M DuPont, A Harbour, J Wright, R Lamendella, BR Stevens, GY Oudit, MB Grant Plasma Microbiome in COVID-19 Subjects: An Indicator of Gut Barrier Defects and Dysbiosis International Journal of Molecular Sciences, 2022-08-15;23(16):. 2022-08-15 [PMID: 36012406] (Human)		Human
MM Hasan, MA Gazi, S Das, SM Fahim, F Hossaini, AR Khan, J Ferdous, MA Alam, M Mahfuz, T Ahmed Gut biomolecules (I-FABP, TFF3 and lipocalin-2) are associated with linear growth and biomarkers of environmental enteric dysfunction (EED) in Bangladeshi children Scientific Reports, 2022-08-16;12(1):13905. 2022-08-16 [PMID: 35974137] (Human)		Human
A Gandini, T De Maayer, C Munien, K Bertrand, R Cairns, A Mayne, MP Gededzha, ES Mayne Intestinal fatty acid binding protein (I-FABP) and CXC3L1 evaluation as biomarkers for patients at high-risk for coeliac disease in Johannesburg, South Africa Cytokine, 2022-07-13;157(0):155945. 2022-07-13 [PMID: 35841826] (Human)		Human
M Logan, M MacKinder, CM Clark, A Kountouri, M Jere, UZ Ijaz, R Hansen, P McGrogan, RK Russell, K Gerasimidi Intestinal fatty acid binding protein is a disease biomarker in paediatric coeliac disease and Crohn's disease BMC gastroenterology, 2022-05-23;22(1):260. 2022-05-23 [PMID: 35606704] (Human)		Human
Y Wang, K Dan, X Xue, X Yang, X Feng, Q Yang, J Yang, B Chen Translocating lipopolysaccharide correlates with the severity of enterovirus A71-induced HFMD by promoting pro-inflammation and viral IRES activity Gut pathogens, 2021-11-22;13(1):69. 2021-11-22 [PMID: 34809671] (Human)		Human
V Feng, KK Bawa, S Marzolini, A Kiss, P Oh, N Herrmann, KL Lanctôt, D Gallagher Impact of 12-week exercise program on biomarkers of gut barrier integrity in patients with coronary artery disease PLoS ONE, 2021-11-19;16(11):e0260165. 2021-11-19 [PMID: 34797867] (Human)		Human
K Schei, MR Simpson, T Øien, S Salamati, K Rudi, RA Ødegård Allergy-related diseases and early gut fungal and bacterial microbiota abundances in children Clinical and translational allergy, 2021-06-28;11(5):e12041. 2021-06-28 [PMID: 34194728] (Human)		Human
JM Keane, AS Khashan, FP McCarthy, LC Kenny, JM Collins, SM O'Donovan, JR Brown, JF Cryan, TG Dinan, G Clarke, SM O'Mahony Identifying a biological signature of prenatal maternal stress JCI Insight, 2021-01-25;0(0):. 2021-01-25 [PMID: 33301421] (Human)		Human
A Wiedemann, E Foucat, H Hocini, C Lefebvre, BP Hejblum, M Durand, M Krüger, AK Keita, A Ayouba, S Mély, JC Fernandez, A Touré, S Fourati, C Lévy-March, H Raoul, E Delaporte, L Koivogui, R Thiébaut, C Lacabaratz, Y Lévy Long-lasting severe immune dysfunction in Ebola virus disease survivors Nat Commun, 2020-07-24;11(1):3730. 2020-07-24 [PMID: 32709840] (Human)		Human
KA Krychtiuk, B Richter, M Lenz, P Hohensinne, K Huber, C Hengstenbe, J Wojta, G Heinz, WS Speidl Epinephrine treatment but not time to ROSC is associated with intestinal injury in patients with cardiac arrest Resuscitation, 2020-06-06;0(0):. 2020-06-06 [PMID: 32522698] (Human)		Human
LB Giron, CE Tanes, MH Schleimann, PA Engen, LM Mattei, A Anzurez, M Damra, H Zhang, K Bittinger, F Bushman, A Kossenkov, PW Denton, H Tateno, A Keshavarzi, AL Landay, M Abdel-Mohs Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection Mucosal Immunol, 2020-03-09;0(0):. 2020-03-09 [PMID: 32152415] (Human)		Human
A Shieh, M Epeldegui, AS Karlamangl, GA Greendale Gut permeability, inflammation, and bone density across the menopause transition JCI Insight, 2020-01-30;0(0):. 2020-01-30 [PMID: 31830000] (Human)		Human
RH Bartels, E Chimwezi, V Watson, L Pei, I Potani, B Allubha, K Chidzalo, D Wang, Q Dube, M Mallewa, A Allen, RHJ Bandsma, WP Voskuijl, SJ Allen Hypoallergenic and anti-inflammatory feeds in children with complicated severe acute malnutrition: an open randomised controlled 3-arm intervention trial in Malawi Sci Rep, 2019-02-19;9(1):2304. 2019-02-19 [PMID: 30783173] (Human)		Human
E G Peters Relation between postoperative ileus and anastomotic leakage after colorectal resection: a post hoc analysis of a prospective randomized controlled trial Colorectal Dis, 2017-07-01;0(0):. 2017-07-01 [PMID: 27943617] (Human)		Human
Show All 28 Publications. Collapse Publications.

Array DFBP20

• FABP2/I-FABP Antibodies
• FABP2/I-FABP ELISA Kits
• FABP2/I-FABP Lysate
• FABP2/I-FABP Proteins
• FABP2/I-FABP ELISAs
• FABP2/I-FABP Proteins and Enzyme