Human CD117/c-kit DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CD117, also known as c-kit and SCF R, is the cellular receptor for Stem Cell Factor (SCF), also named c-kit ligand, mast cell growth factor, and steel factor. This receptor-ligand system plays essential roles in germ cell development, melanogenesis, hematopoiesis, and oncogenesis. CD117 is expressed on lymphoid, myeloid, erythroid, and megakaryocyte progenitors, NK cells, germ cells, melanocytes, glial cells, vascular smooth muscle cells, placenta, and epithelial cells. Altered levels and mutations in CD117 are associated with several types of cancer including lung, breast, gastrointestinal stromal, and germ cell tumors.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 3 of 3.

Publications using DY332	Applications	Species
A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts Cell Reports, 2023-04-28;42(5):112453. 2023-04-28 [PMID: 37120813] (Human)		Human
DePrimo SE, Huang X, Blackstein ME, Garrett CR, Harmon CS, Schoffski P, Shah MH, Verweij J, Baum CM, Demetri GD Circulating levels of soluble KIT serve as a biomarker for clinical outcome in gastrointestinal stromal tumor patients receiving sunitinib following imatinib failure. Clin. Cancer Res., 2009-09-08;15(18):5869-77. 2009-09-08 [PMID: 19737953] (Human)		Human
Massa M, Rosti V, Ferrario M, Campanelli R, Ramajoli I, Rosso R, De Ferrari GM, Ferlini M, Goffredo L, Bertoletti A, Klersy C, Pecci A, Moratti R, Tavazzi L Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction. Blood, 2004-09-02;105(1):199-206. 2004-09-02 [PMID: 15345590] (Human)		Human

Array DY332

• CD117/c-kit Antibodies
• CD117/c-kit ELISA Kits
• CD117/c-kit Lysates
• CD117/c-kit Proteins
• CD117/c-kit ELISAs
• CD117/c-kit Proteins and Enzymes