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HTRA2/Omi Antibody (1B3) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1B3
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-04325AF350
Alexa Fluor 405
NBP1-04325AF405
Alexa Fluor 488
NBP1-04325AF488
Alexa Fluor 532
NBP1-04325AF532
Alexa Fluor 594
NBP1-04325AF594
Alexa Fluor 647
NBP1-04325AF647
Alexa Fluor 700
NBP1-04325AF700
Alexa Fluor 750
NBP1-04325AF750
Biotin
NBP1-04325B
CoraFluor 1
NBP1-04325CL1
DyLight 350
NBP1-04325UV
DyLight 405
NBP1-04325V
DyLight 488
NBP1-04325G
DyLight 550
NBP1-04325R
DyLight 594
NBP1-04325DL594
DyLight 650
NBP1-04325C
DyLight 680
NBP1-04325FR
DyLight 755
NBP1-04325IR
FITC
NBP1-04325F
HRP
NBP1-04325H
Janelia Fluor 525
NBP1-04325JF525
Janelia Fluor 549
NBP1-04325JF549
Janelia Fluor 635
NBP1-04325JF635
Janelia Fluor 646
NBP1-04325JF646
Janelia Fluor 669
NBP1-04325JF669
Unconjugated
NBP1-04325
mFluor Violet 450 SE
NBP1-04325MFV450
mFluor Violet 500 SE
NBP1-04325MFV500
mFluor Violet 610 SE
NBP1-04325MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-04325
BSA Free
NBP1-04325
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HTRA2/Omi Antibody (1B3) [Janelia Fluor® 585] Summary

Immunogen
Recombinant human HtrA2/Omi (134-458 aa) purified from E. coli
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HTRA2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HTRA2/Omi Antibody (1B3) [Janelia Fluor® 585]

  • High temperature requirement protein A2
  • HtrA serine peptidase 2
  • HTRA2
  • HtrA-like serine protease
  • Omi
  • OMIOmi stress-regulated endoprotease
  • PARK13EC 3.4.21.108
  • PRSS25
  • PRSS25serine, 25
  • Serine protease 25
  • serine protease HTRA2, mitochondrial
  • Serine proteinase OMI

Background

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HTRA2/Omi Antibody
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NBP1-04325JF585
HTRA2/Omi Antibody (1B3) [Janelia Fluor® 585]
Species: Hu
Applications: WB, ELISA

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Bioinformatics

Gene Symbol HTRA2