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HTRA2/Omi Antibody (196C429) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
196C429
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56558AF350
Alexa Fluor 405
NB100-56558AF405
Alexa Fluor 488
NB100-56558AF488
Alexa Fluor 532
NB100-56558AF532
Alexa Fluor 594
NB100-56558AF594
Alexa Fluor 647
NB100-56558AF647
Alexa Fluor 700
NB100-56558AF700
Alexa Fluor 750
NB100-56558AF750
Biotin
NB100-55789
DyLight 350
NB100-56558UV
DyLight 405
NB100-56558V
DyLight 488
NB100-56558G
DyLight 550
NB100-56558R
DyLight 594
NB100-56558DL594
DyLight 650
NB100-56558C
DyLight 680
NB100-56558FR
DyLight 755
NB100-56558IR
FITC
NB100-56558F
HRP
NB100-56558H
Unconjugated
NB100-56558
mFluor Violet 450 SE
NB100-56558MFV450
mFluor Violet 500 SE
NB100-56558MFV500
mFluor Violet 610 SE
NB100-56558MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56558
Azide and BSA Free
NBP2-80782
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HTRA2/Omi Antibody (196C429) [Biotin] Summary

Immunogen
This monoclonal antibody was developed by immunizing mice with a synthetic peptide containing amino acids 335-350 of human HtrA2.
Specificity
This antibody does not cross-react with mouse HtrA2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HTRA2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for HTRA2/Omi Antibody (196C429) [Biotin]

  • High temperature requirement protein A2
  • HtrA serine peptidase 2
  • HTRA2
  • HtrA-like serine protease
  • Omi
  • OMIOmi stress-regulated endoprotease
  • PARK13EC 3.4.21.108
  • PRSS25
  • PRSS25serine, 25
  • Serine protease 25
  • serine protease HTRA2, mitochondrial
  • Serine proteinase OMI

Background

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HTRA2/Omi Antibody
(196C429) [Biotin]
NB100-56558B
HTRA2/Omi Antibody (196C429) [Biotin]
Species: Hu
Applications: WB, IHC
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Bioinformatics

Gene Symbol HTRA2