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HLA DQA1 Antibody (7W0M7)

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Western Blot: HLA DQA1 Antibody (7W0M7) [NBP3-15364] - Western blot analysis of extracts of various cell lines, using HLA DQA1 Rabbit mAb (NBP3-15364) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG ...read more
Immunohistochemistry-Paraffin: HLA DQA1 Antibody (7W0M7) [NBP3-15364] - Immunohistochemistry of paraffin-embedded mouse spleen using HLA DQA1 Rabbit mAb (NBP3-15364) at dilution of 1:100 (40x lens).Perform microwave ...read more
Immunohistochemistry-Paraffin: HLA DQA1 Antibody (7W0M7) [NBP3-15364] - Immunohistochemistry of paraffin-embedded rat spleen using HLA DQA1 Rabbit mAb (NBP3-15364) at dilution of 1:100 (40x lens).Perform microwave ...read more
Immunohistochemistry-Paraffin: HLA DQA1 Antibody (7W0M7) [NBP3-15364] - Immunohistochemistry of paraffin-embedded human spleen using HLA DQA1 Rabbit mAb (NBP3-15364) at dilution of 1:100 (40x lens).Perform microwave ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
7W0M7
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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HLA DQA1 Antibody (7W0M7) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 155-254 of human HLA DQA1 (P01909). EGVSETSFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVFIIRGLRSVGASRHQGPL
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HLA-DQA1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for HLA DQA1 Antibody (7W0M7)

  • CD
  • CELIAC1DQ alpha 1 chain
  • DC-1 alpha chain
  • DQ-A1
  • FLJ27088
  • FLJ27328
  • GSE
  • HLA class II histocompatibility antigen, DQ(W3) alpha chain
  • HLA-DCA
  • HLA-DQA
  • leucocyte antigen DQA1
  • leukocyte antigen alpha chain
  • major histocompatibility complex, class II, DQ alpha 1
  • MGC149527
  • MHC class II antigen
  • MHC class II DQA1
  • MHC class II HLA-D alpha glycoprotein
  • MHC class II HLA-DQ-alpha-1
  • MHC class II surface glycoprotein
  • MHC HLA-DQ alpha

Background

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HLA-DQA1