Name: HGF Antibody (24612) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB294
Price: 489 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, IHC, B/N
Clone	24612
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Formulation	Size	Price
Carrier Free MAB294-SP

Carrier Free MAB294-500

Immunogen	S. frugiperda insect ovarian cell line Sf 21-derived recombinant human HGF Gln32-Ser728 (Asp384Asn, Asp416Asn, Leu622Ser, His645Arg, Val678Ile) Accession # P14210
Specificity	Detects human HGF in Western blots. In Western blots, no-cross reactivity with recombinant mouse HGF or recombinant canine HGF is observed.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	HGF
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

HGF Antibody (24612) [Unconjugated]

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HGF Antibody (24612) [Unconjugated] Summary

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Publications for HGF Antibody (MAB294)(32)

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Bioinformatics

Publications using MAB294	Applications	Species
Y Deng, Z Zhao, M Sheldon, Y Zhao, H Teng, C Martinez, J Zhang, C Lin, Y Sun, F Yao, H Zhu, L Ma LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration bioRxiv : the preprint server for biology, 2023-03-21;0(0):. 2023-03-21 [PMID: 36993315] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
F Kano, N Hashimoto, Y Liu, L Xia, T Nishihara, W Oki, K Kawarabaya, N Mizusawa, K Aota, T Sakai, M Azuma, H Hibi, T Iwasaki, T Iwamoto, N Horimai, A Yamamoto Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia Scientific Reports, 2023-02-15;13(1):2706. 2/15/2023 [PMID: 36792628]
HH Jang, Y Son, G Park, KS Park Bone Marrow-Derived Vasculogenic Mesenchymal Stem Cells Enhance In Vitro Angiogenic Sprouting of Human Umbilical Vein Endothelial Cells International Journal of Molecular Sciences, 2022-12-27;24(1):. 2022-12-27 [PMID: 36613857] (Bioassay, Human)	Bioassay	Human
P Uruski, J Miku?a-Pie, M Paku?a, S Budkiewicz, M Drzewiecki, AN Gaiday, M Wierzowiec, E Naumowicz, R Moszy?ski, A Tykarski, K Ksi??ek Malignant Ascites Promote Adhesion of Ovarian Cancer Cells to Peritoneal Mesothelium and Fibroblasts International Journal of Molecular Sciences, 2021-04-19;22(8):. 4/19/2021 [PMID: 33921783]
Bin Chen, Tuo Cai, Chao Huang, Xueyan Zang, Li Sun, Shuwei Guo et al. G6PD-NF-kappa B-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2 Frontiers in Oncology 2021-02-26 [PMID: 33718248]
2020-12-17;0(0):. 2020-12-17 [PMID: 33348564] (Western Blot, Human)	Western Blot	Human
M Paku?a, E Ma?y, P Uruski, A Witucka, M Bogucka, N Jaroszewsk, N Makowska, A Niklas, R Moszy?ski, S Sajdak, A Tykarski, J Miku?a-Pie, K Ksi??ek Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells Cancers (Basel), 2020-01-27;12(2):. 2020-01-27 [PMID: 32012719] (Neutralization, Human)	Neutralization	Human
M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 2019-05-13;11(5):. 2019-05-13 [PMID: 31086083] (Neutralization, Human)	Neutralization	Human
Jeremy A. Lavine, Michael S. Ramos, Alyson M. Wolk, Kimberly Baynes, Sumit Sharma, Aleksandra V. Rachitskaya et al. Heterogeneity of cultured melanocyte elongation and proliferation factor in bilateral diffuse uveal melanocytic proliferation Experimental Eye Research 2019-07-01 [PMID: 30978346]
M Paku?a, J Miku?a-Pie, A Witucka, K Kostka-Jez, P Uruski, R Moszy?ski, E Naumowicz, S Sajdak, A Tykarski, K Ksi??ek The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells Int J Mol Sci, 2019-01-02;20(1):. 2019-01-02 [PMID: 30609691] (Neutralization, Human)	Neutralization	Human
L Rao, K De Veirman, D Giannico, I Saltarella, V Desantis, MA Frassanito, AG Solimando, D Ribatti, M Prete, A Harstrick, U Fiedler, H De Raeve, V Racanelli, K Vanderkerk, A Vacca Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPinï¿½ protein MP0250: a preclinical study Oncotarget, 2018-01-30;9(17):13366-13381. 2018-01-30 [PMID: 29568363] (Neutralization, Human)	Neutralization	Human
Chisato Tomida, Naoko Yamagishi, Hikaru Nagano, Takayuki Uchida, Ayako Ohno, Katsuya Hirasaka et al. VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells International Journal of Oncology 2018-02-28 [PMID: 29532881]
Vegard Tjomsland, Monica Aasrum, Thoralf Christoffersen, Ivar P Gladhaug Functional heterogeneity in tumor-derived human pancreatic stellate cells: Differential expression of HGF and implications for mitogenic signaling and migration in pancreatic cancer cells Oncotarget 2017-09-22 [PMID: 29069737]
Yong Qin, Jason Roszik, Chandrani Chattopadhyay, Yuuri Hashimoto, Chengwen Liu, Zachary A. Cooper et al. Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma Molecular Cancer Therapeutics 2016-10-01 [PMID: 27458138]
Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. PLoS ONE, 2015-04-28;10(4):e0124283. 2015-04-28 [PMID: 25919140] (Bioassay, Human)	Bioassay	Human
Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts. Br J Cancer, 2015-04-16;112(10):1675-86. 2015-04-16 [PMID: 25880005] (Bioassay, Human)	Bioassay	Human
Grzegorz Przybylski, Joanna Chorostowska-Wynimko, Andrzej Dyczek, Ewelina Wędrowska, Marek Jankowski, Adam Szpechciński et al. Studies of hepatocyte growth factor in bronchoalveolar lavage fluid in chronic interstitial lung diseases Polish Archives of Internal Medicine 2015-02-21 [PMID: 25697336]
Aenlle K, Curtis K, Roos B, Howard G Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells. Mol Endocrinol, 2014-03-27;28(5):722-30. 2014-03-27 [PMID: 24673557] (Neutralization, Human)	Neutralization	Human
Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell, 2014-03-06;14(3):342-56. 2014-03-06 [PMID: 24607406] (Functional Assay, Human)	Functional Assay	Human
Julin S. Wong, Emma Warbrick, Borek Vojtesek, Jeffrey Hill, David P. Lane Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth Oncotarget 2013-06-29 [PMID: 23859937]
Ravid Straussman, Teppei Morikawa, Kevin Shee, Michal Barzily-Rokni, Zhi Rong Qian, Jinyan Du et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion Nature 2012-07-26 [PMID: 22763439]
Pavel Makarevich, Zoya Tsokolaeva, Alexander Shevelev, Igor Rybalkin, Evgeny Shevchenko, Irina Beloglazova et al. Combined Transfer of Human VEGF165 and HGF Genes Renders Potent Angiogenic Effect in Ischemic Skeletal Muscle PLoS ONE 2012-06-13 [PMID: 22719942]
Valgardur Sigurdsson, Bylgja Hilmarsdottir, Hekla Sigmundsdottir, Agla J. R. Fridriksdottir, Markus Ringnér, Rene Villadsen et al. Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties PLoS ONE 2011-09-06 [PMID: 21915264]
Tyan SW, Kuo WH, Huang CK Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis. PLoS ONE, 2011-01-13;6(1):e15313. 2011-01-13 [PMID: 21249190] (Neutralization, Western Blot, Human)	Neutralization, Western Blot	Human
Schipper HS, De Jager W, van Dijk ME, Meerding J, Zelissen PM, Adan RA, Prakken BJ, Kalkhoven E A multiplex immunoassay for human adipokine profiling. Clin. Chem., 2010-06-08;56(0):1320. 2010-06-08 [PMID: 20530731] (Luminex Development, Human)	Luminex Development	Human
Mihyun H. Bae, Gregory B. Bissonette, Wendy M. Mars, George K. Michalopoulos, Cristian L. Achim, Didier A. Depireux et al. Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility Experimental Neurology 2010-01-01 [PMID: 19853606]
Coxon A, Rex K, Meyer S, Sun J, Sun J, Chen Q, Radinsky R, Kendall R, Burgess TL Soluble c-Met receptors inhibit phosphorylation of c-Met and growth of hepatocyte growth factor: c-Met-dependent tumors in animal models. Mol. Cancer Ther., 2009-05-12;0(0):. 2009-05-12 [PMID: 19435874] (Neutralization, Human)	Neutralization	Human
Marsh D, Dickinson S, Neill GW, Marshall JF, Hart IR, Thomas GJ alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer Res., 2008-05-01;68(9):3295-303. 2008-05-01 [PMID: 18451156] (ICC, Human)	ICC	Human
Hatfield K, Ryningen A, Corbascio M, Bruserud O Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int. J. Cancer, 2006-11-15;119(10):2313-21. 2006-11-15 [PMID: 16921487] (Neutralization, Human)	Neutralization	Human
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J. Immunol., 2005-11-01;175(9):6177-89. 2005-11-01 [PMID: 16237115] (Neutralization, Human)	Neutralization	Human
Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res., 2003-02-15;63(4):887-92. 2003-02-15 [PMID: 12591743] (Flow Cytometry, Human)	Flow Cytometry	Human
Takayama K, Suzuki J, Kawauchi M, Tsukioka K, Wada Y, Zhang T, Endoh M, Takamoto S, Amano J, Isobe M Hepatocyte growth factor and vascular endothelial growth factor expression in pig-to-primate xenotransplanted hearts. Transplant. Proc., 2000-08-01;32(5):987-9. 2000-08-01 [PMID: 10936314] (IHC-P, Porcine)	IHC-P	Porcine
Show All 32 Publications. Collapse Publications.

Gene Symbol	HGF
Uniprot	P14210()