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HBS1L Antibody (OTI1C1)

Images

 
Western Blot: HBS1L Antibody (1C1) [NBP2-45934] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HBS1L.
Immunohistochemistry: HBS1L Antibody (1C1) [NBP2-45934] - Analysis of Carcinoma of Human lung tissue.
Immunohistochemistry: HBS1L Antibody (1C1) [NBP2-45934] - Analysis of Human breast tissue.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI1C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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HBS1L Antibody (OTI1C1) Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-260 of human HBS1L (NP_006611) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HBS1L
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500
  • Immunohistochemistry-Paraffin 1:500
  • Western Blot 1:2000
Theoretical MW
75.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HBS1L Antibody (OTI1C1)

  • DKFZp434g247
  • ERF3-similar protein
  • ERFSDKFZp686L13262
  • HBS1 (S. cerevisiae)-like
  • HBS1KIAA1038EF-1a
  • HBS1-like (S. cerevisiae)
  • HBS1-like protein
  • Hsp70 subfamily B suppressor 1-like protein
  • HSPC276

Background

HBS1L encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HBS1L