HAAO Antibody (4D1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using H00023498-M05	Applications	Species
Bai F, Tian H, Ma J et al. Advanced treatment of sewage by membrane bioreactor associate with genetically engineered autotrophic nitrifying bacteria. Bioresour Technol. 2019-04-11 [PMID: 31129517]

Array H00023498-M05

• HAAO Antibodies
• HAAO Lysate
• HAAO Proteins