Reactivity | HuSpecies Glossary |
Applications | Flow, CyTOF-ready |
Clone | 189702 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | NS0 mouse myeloma cell line transfected with human GPR39 Met1-Val453 Accession # BAG37409 |
Specificity | Detects human GPR39. Stains human GPR39-transfected cells but not irrelevant transfectants. |
Isotype | IgG2a |
Clonality | Monoclonal |
Host | Mouse |
Gene | GPR39 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane glycoprotein and a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39.
Secondary Antibodies |
Isotype Controls |
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