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Glutathione Peroxidase 4/GPX4 Antibody (LHM 2) [mFluor Violet 610 SE]

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Glutathione Peroxidase 4/GPX4 Antibody (LHM 2) [mFluor Violet 610 SE] [NBP3-08253MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ELISA, Flow, ICC/IF, IHC
Clone
LHM 2
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

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Glutathione Peroxidase 4/GPX4 Antibody (LHM 2) [mFluor Violet 610 SE] Summary

Immunogen
A 375P cells crude extract
Localization
Mitochondrion, Cytoplasm
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GPX4
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Glutathione Peroxidase 4/GPX4 Antibody (LHM 2) [mFluor Violet 610 SE]

  • EC 1.11.1
  • EC 1.11.1.12
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • Glutathione Peroxidase 4
  • GPX4
  • GPx-4
  • GSHPx-4
  • MCSP
  • PHGPx
  • PHGPxsnGPx
  • phospholipid hydroperoxidase
  • phospholipid hydroperoxide glutathione peroxidase, mitochondrial
  • snGPx
  • snPHGPx
  • sperm nucleus glutathione peroxidase

Background

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glutathione Peroxidase 4/GPX4 Antibody (NBP3-08253MFV610) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Glutathione Peroxidase 4/GPX4 Antibody (NBP3-08253MFV610) (0)

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Secondary Antibodies

 

Isotype Controls

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol GPX4