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Glutamate Receptor 6 Antibody (818235) [PE/Atto594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
818235
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Atto594

Order Details

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Glutamate Receptor 6 Antibody (818235) [PE/Atto594] Summary

Immunogen
Chinese Hamster Ovary cell line CHO-derived human GluR6/GRIK2 protein
Thr32 - Asn549
Accession # Q13002
Specificity
Detects human GluR6/GRIK2 in cell-based ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Glutamate Receptor 6 Antibody (818235) [PE/Atto594]

  • EAA4
  • GLR6
  • GluK2
  • GLUK6
  • GluR6
  • glutamate receptor 6
  • glutamate receptor, ionotropic, kainate 2
  • ionotropic kainate 2
  • MGC74427
  • MRT6

Background

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem, whereas the four epsilon subunits display limited distribution.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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