GluR5/GRIK1 Antibody

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NB100-68165	Applications	Species
Martin S, Nishimune A, Mellor JR, Henley JM. SUMOylation regulates kainate-receptor-mediated synaptic transmission. Nature 2007-05-17 [PMID: 17486098]
Christensen JK, Paternain AV, Selak S et al. A mosaic of functional kainate receptors in hippocampal interneurons. J Neurosci 2004-10-01 [PMID: 15483117]

Array NB100-68165

• GluR5/GRIK1 Antibodies
• GluR5/GRIK1 Lysate
• GluR5/GRIK1 Proteins