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Glucuronic Acid Epimerase Antibody

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Western Blot: Glucuronic Acid Epimerase Antibody [NBP2-87507] - Host: Rabbit. Target Name: GLCE. Sample Tissue: Human Jurkat Whole Cell lysates. Antibody Dilution: 1ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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Glucuronic Acid Epimerase Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human Glucuronic Acid Epimerase. Peptide sequence: TKDHIFLNSALRATAPYKFLSEQHGVKAVFMNKHDWYEEYPTTPSSFVLN The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
GLCE
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Glucuronic Acid Epimerase Antibody

  • D-glucuronyl C5-epimerase
  • EC 5.1.3
  • EC 5.1.3.-
  • glucuronic acid epimerase
  • glucuronyl C5-epimerase
  • Heparin/heparan sulfate:glucuronic acid C5-epimerase
  • HSEPIheparin/heparan sulfate-glucuronic acid C5-epimerase
  • KIAA0836heparan sulfate epimerase
  • UDP-glucuronic acid epimerase

Background

Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GLCE