S100A4 Antibody (1F12-1G7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: ICC/IF, IF/IHC, WB.

Showing Publications 1 - 10 of 17. Show All 17 Publications. Collapse Publications.

Publications using H00006275-M01	Applications	Species
Singh S, Adam M, Matkar P et al. Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis. Sci Rep. 2020-03-11 [PMID: 32161282]
Kan C, Ding N, Yang J et al. BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification. Stem Cell Res Ther 2019-01-11 [PMID: 30635039] (ICC/IF, Mouse)	ICC/IF	Mouse
Liu T, Ma W, Xu H et al. PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma. Nat Commun 2018-08-27 [PMID: 30150753]
Hou X, Zhang J, Wang Y et al. TGFBR-IDH1-Cav1 axis promotes TGF-? signalling in cancer-associated fibroblast. Oncotarget. 2017-10-13 [PMID: 29137396]
Kan C, Chen L, Hu Y et al. Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification. Bone. 2017-06-21 [PMID: 28645539]
Cosme J, Guo H, Hadipour-Lakmehsari S et al. Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice. J Proteome Res 2017-06-22 [PMID: 28641008]
Lin SC, Lee YC, Yu G et al. Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer. Dev Cell 2017-06-05 [PMID: 28586644]
Singh KK, Lovren F, Pan Y et al. The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition. J Biol Chem 2015-01-30 [PMID: 25527499] (WB)	WB
Volonte A, Di Tomaso T, Spinelli M et al. Cancer-Initiating Cells from Colorectal Cancer Patients Escape from T Cell-Mediated Immunosurveillance In Vitro through Membrane-Bound IL-4. J Immunol. 2013-11-25 [PMID: 24277698]
Birbrair A, Zhang T, Wang ZM et al. Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle. Am J Physiol Cell Physiol 2013-12-01 [PMID: 24067916] (ICC/IF, IF/IHC, Mouse)	ICC/IF, IF/IHC	Mouse
Li Q, Zhang D, Wang Y et al. MiR-21/Smad 7 signaling determines TGF-b1-induced CAF formation. Sci Rep. 2013-01-01 [PMID: 23784029]
Kan L, Peng CY, McGuire TL, Kessler JA et al. Glast-expressing progenitor cells contribute to heterotopic ossification Bone 2012-12-20 [PMID: 23262027] (ICC/IF, IF/IHC, Mouse)	ICC/IF, IF/IHC	Mouse
Chen Y, Huang K, Nakatsu MN et al. Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells. Hum Mol Genet. 2013-01-08 [PMID: 23257286]
Swift-Gallant A, Monks DA. Androgen receptor expression in satellite cells of the neonatal levator ani of the rat. Dev Neurobiol. 2012-12-12 [PMID: 23239638]
Nishioku T, Furusho K, Tomita A et al. Potential role for S100A4 in the disruption of the blood-brain barrier in collagen-induced arthritic mice, an animal model of rheumatoid arthritis. Neuroscience. 2011-05-26 [PMID: 21627981]
Zeisberg, EM et al. Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts. Cancer Res 67: 10123-10128. 2007-01-01 [PMID: 17974953]
Chen PS, Wang MY, Wu SN et al. CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway. J Cell Sci 2007-06-15 [PMID: 17550972]
Show All 17 Publications. Collapse Publications.

Array H00006275-M01

• S100A4 Antibodies
• S100A4 ELISA Kit
• S100A4 Lysates
• S100A4 Proteins
• S100A4 Proteins and Enzymes