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Galanin R2/GALR2 Antibody (616520) [Unconjugated]

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HEK293 human embryonic kidney cell line transfected with human Galanin R2/GALR2 and eGFP was stained with either (A) Mouse Anti-Human Galanin R2/GALR2 Monoclonal Antibody (Catalog # MAB6544) followed by ...read more
Galanin R2 was detected in immersion fixed paraffin-embedded sections of human brain (hippocampus) using Human Galanin R2 Monoclonal Antibody (Catalog # MAB6544) at 25 µg/mL overnight at 4 °C. Tissue was stained using ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
616520
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Galanin R2/GALR2 Antibody (616520) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Galanin R2
Accession # O43603
Specificity
Detects human GAL-R2 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
GALR2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 8-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Galanin R2/GALR2 Antibody (616520) [Unconjugated]

  • GAL2R
  • GAL2-R
  • Galanin R2
  • galanin receptor 2
  • galanin receptor type 2
  • GalaninR2
  • GALNR2
  • GALNR2MGC125984
  • GALR2
  • GALR-2
  • MGC125983

Background

GALR2 (Galanin Receptor 2) is one of three 54-60 kDa G-protein coupled multipass transmembrane receptors for the Galanin neuropeptide. Galanin is co-expressed with and modulates noradrenaline and serotonin systems. GALR2 is thought to modulate growth and apoptosis. Unlike GALR and GALR3, it is thought to be anti-depressive. GALR2 mRNA is found mainly in the central nervous system (except for cerebral cortex), but also in intestine, heart, kidney, liver and many cancers. The combined extracellular domains of human GALR2 share 82% and 86% amino acid identity with mouse and rat GALR2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GALR2
Uniprot