Proximity Ligation Assay: GADD45 alpha Antibody (3D12) [H00001647-M01] - Analysis of protein-protein interactions between MAP2K6 and GADD45A. HeLa cells were stained with anti-MAP2K6 rabbit purified polyclonal 1:1200 ...read more
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
GADD45A (AAH11757, 76 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
Specificity
GADD45A - growth arrest and DNA-damage-inducible, alpha
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GADD45A
Purity
IgG purified
Innovator's Reward
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Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.Use in Simple Western reported in scientific literature (PMID:29890265).
Publications
Read Publications using H00001647-M01 in the following applications:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for GADD45 alpha Antibody (3D12)
DDIT-1
DDIT1growth arrest and DNA damage-inducible protein GADD45 alpha
DNA damage-inducible transcript 1 protein
DNA damage-inducible transcript-1
GADD45 alpha
GADD45a
GADD45DNA-damage-inducible transcript 1
growth arrest and DNA-damage-inducible 45 alpha
growth arrest and DNA-damage-inducible, alpha
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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