GABA-AR alpha 5 Antibody

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 3 applications: IF/IHC, IHC-FrFl, WB.

Showing Publications 1 - 6 of 6.

Publications using NB300-195	Applications	Species
Auta J, Locci A, Guidotti A et al. Sex-dependent sensitivity to positive allosteric modulation of GABA action in an APP knock-in mouse model of Alzheimer's disease: Potential epigenetic regulation Current Research in Neurobiology 2021-12-21 [PMID: 36518344] (WB, Mouse)	WB	Mouse
You C, Vandegrift BJ, Zhang H et al. Histone deacetylase inhibitor suberanilohydroxamic acid (SAHA) treatment reverses hyposensitivity to g-aminobutyric acid in the ventral tegmental area during ethanol withdrawal Alcohol. Clin. Exp. Res. 2018-08-13 [PMID: 30103280] (IF/IHC, Rat)	IF/IHC	Rat
Lu CY, Liu D, Jiang H et al. Effects of traumatic stress induced in the juvenile period on the expression of Gamma-aminobutyric acid receptor type A subunits in adult rat brain. Hindawi Neural Plasticity. 2017-03-02 [PMID: 28352479] (IF/IHC, WB, Rat)	IF/IHC, WB	Rat
Botta P, Demmou L, Kasugai Y et al. Regulating anxiety with extrasynaptic inhibition. Nat. Neurosci. 2015-10-01 [PMID: 26322928] (WB, IHC-FrFl, Mouse)	WB, IHC-FrFl	Mouse
Blednov YA, Walker DL, Iyer SV et al. Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol. Addict Biol 2010-01-01 [PMID: 20002022] (WB, Mouse)	WB	Mouse
Pinna, G et al. Imidazenil diazepam increase locomotor activity in mice exposed to protracted social isolation. PNAS. 103:4275-4280. 2006-01-01 [PMID: 16537521] (WB, Mouse)	WB	Mouse

Array NB300-195

• GABA-AR alpha 5 Antibodies
• GABA-AR alpha 5 Lysates
• GABA-AR alpha 5 Protein