G3BP2 Antibody

Ras-GAP SH3 domain binding protein (G3BP2) contains an RNA recognition motif (RRM) and an N-terminal nuclear transport factor 2-like (NTF2-like) domain. The G3BP family of proteins have been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation.G3BP2 can interact with IkappaBalpha and IkappaBalpha/NFkappaB complexes. In this complex G3B2 is proposed to play a role in regulating the nucleocytoplasmic localization of NFkappaB as well as its activity.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 6 applications: ICC/IF, IF/IHC, IHC-P, IP, PLA, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP1-82976	Applications	Species
Wang C, Terrigno M, Li J et al. Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation Neuron 2023-06-23 [PMID: 37385246] (PLA, WB, Human)	PLA, WB	Human
Somasekharan SP, Gleave M SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets FEBS letters 2021-11-15 [PMID: 34780058] (WB, Human)	WB	Human
Li H, Lin PH, Gupta P et al. MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer Molecular cancer 2021-09-14 [PMID: 34521423] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Ramachandran B, Stabley JN, Cheng SL, et al. A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells. J Biol Chem. 2018 Apr 6 [PMID: 29626090] (WB, IP, Human)	WB, IP	Human
De Marchi T, Liu NQ, Stingl C et al. 4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer Molecular Oncology 2016-01-01 [PMID: 26285647]
De Marchi T, Liu NQ, Stingl C et al. 4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer Mol Oncol 2016 Jan 01 [PMID: 26285647] (IHC-P, Human) Details: The Novus G3BP2 antibody was used to look for a potential correlation between increased G3BP2 expression and clinical outcomes.	IHC-P	Human
Wei SC, Fattet L, Tsai JH et al. Matrix stiffness drives Epithelial-Mesenchymal Transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol 2015-05-01 [PMID: 25893917] (WB, IF/IHC, Mouse)	WB, IF/IHC	Mouse

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IF	Mouse	09/01/2017	View Summary Application Immunofluorescence Sample Tested Cortical neurons Species Mouse Lot A104863

Array NBP1-82976

• G3BP2 Antibodies
• G3BP2 Lysate
• G3BP2 Proteins