G3BP1 Antibody (2F3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Monkey.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 8 of 8.

Publications using H00010146-M01	Applications	Species
Ming Z, Tian X, Jia-Qing X et al. The stress granule protein G3BP1 promotes pre-condensation of cGAS to allow rapid responses to DNA. EMBO Rep. 2021-11-15 [PMID: 34779554]
Hong C, Xin L, Feng Z et al. G3BP1 Inhibition Alleviates Intracellular Nucleic Acid-Induced Autoimmune Responses. J Immunol. 2021-05-03 [PMID: 33941659]
Lutz MM th, Worth MP, Hinchman MM et al. Mammalian orthoreovirus Infection is Enhanced in Cells Pre-Treated with Sodium Arsenite Viruses. 2019-06-17 [PMID: 31216693] (ICC/IF, WB, Monkey)	ICC/IF, WB	Monkey
Liu ZS, Cai H, Xue W et al. G3BP1 promotes DNA binding and activation of cGAS. Nat Immunol 2018-12-03 [PMID: 30510222]
Martin S, Bellora N, Gonzalez-Vallinas J et al. Preferential Binding of a stable G3BP Ribonucleoprotein Complex to Intron-retaining Transcripts in Mouse Brain and Modulation of their Expression in the Cerebellum. J Neurochem 2016-08-11 [PMID: 27513819]
Kaehler C, Isensee J, Hucho T et al. 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res. 2014-04-11 [PMID: 24728989]
Martin S, Zekri L, Metz A et al. Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons. J Neurochem. 2013-02-04 [PMID: 23373770]
Norazit A, Meedeniya AC, Nguyen MN, Mackay-Sim A. Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. Brain Res 1360:119-29. 2010-11-11 [PMID: 20807515]

Array H00010146-M01

• G3BP1 Antibodies
• G3BP1 Lysates
• G3BP1 Proteins