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G-CSFR/CD114 Antibody (38660) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
38660
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

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G-CSFR/CD114 Antibody (38660) [Janelia Fluor® 549] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human G‑CSF R/CD114
Glu25-Pro621
Accession # Q99062
Specificity
Detects human G‑CSF R/CD114 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) GM-CSF R alpha , rhGM-CSF R beta , or rhM-CSF R is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CSF3R
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for G-CSFR/CD114 Antibody (38660) [Janelia Fluor® 549]

  • CD114 antigen
  • CD114
  • colony stimulating factor 3 receptor (granulocyte)
  • CSF3R
  • Csfgr
  • G-CSF R
  • G-CSF receptor
  • GCSFR
  • G-CSFR
  • GCSFRG-CSF-R
  • granulocyte colony-stimulating factor receptor

Background

GCSF Receptor is encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSF3R