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FOXO1A/3/4 Antibody (14E4)

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Immunocytochemistry/Immunofluorescence: FOXO1A/3/4 Antibody (14E4) [NBP1-41195] - Analysis of paraformaldehyde-fixed HeLa, antibody at 1:100 dilution.
Immunocytochemistry/ Immunofluorescence: FOXO1A/3/4 Antibody (14E4) [NBP1-41195] - Analysis of paraformaldehyde-fixed HeLa, antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clone
14E4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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FOXO1A/3/4 Antibody (14E4) Summary

Immunogen
Amino acids 242-655 of FKHR expressed in E. coli.
Specificity
This antibody will recognize human FKHR.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
FOXO1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Western Blot 0.1-2 ug/ml
Application Notes
WB: Predicted MW is 70 kDa.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Alternate Names for FOXO1A/3/4 Antibody (14E4)

  • FKH1
  • FKHRforkhead box protein O1
  • forkhead box O1
  • Forkhead box protein O1A
  • forkhead homolog in rhabdomyosarcoma
  • Forkhead in rhabdomyosarcoma
  • FOXO1Aforkhead, Drosophila, homolog of, in rhabdomyosarcoma

Background

FKHR-14E4 recognizes FKHR (ForKHead in Rhabdomyosarcoma), a 70a protein, which is one member in a subfamily of the forkhead homeotic gene family of transcription factors. Recent experiments have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FOXO1
Entrez