FoxO1/FKHR Antibody (597554) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FoxO1, also called FKHR (forkhead in ­rhabdomyosarcoma), is a 655 amino acid (aa), 70 kDa, ubiquitously expressed member of the forkhead box O family of winged helix transcription factors. In neurons, it is activated in response to stress, translocating to the nucleus where it promotes apoptosis and blocks proliferation. In insulin-responsive tissues, nutrient abundance triggers phosphorylation by AKT that blocks nuclear translocation and activity. A 60 kDa form, cleaved at R537, has been found in androgen-treated prostate cancer cells. Over aa 353-655, human FoxO1 shares 93% aa identity with mouse and rat FoxO1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC.

Showing Publication 1 - 1 of 1.

Publication using MAB5939	Applications	Species
Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy Proc. Natl. Acad. Sci. U.S.A, 2016-12-12;0(0):. 2016-12-12 [PMID: 27956610] (ICC, Human)	ICC	Human

Array MAB5939

• FoxO1/FKHR Antibodies
• FoxO1/FKHR ELISA Kits
• FoxO1/FKHR Lysate
• FoxO1/FKHR Proteins