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Flt-3/Flk-2/CD135 Antibody (7E8.2C8) [mFluor Violet 500 SE]

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Flt-3/Flk-2/CD135 Antibody (7E8.2C8) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.
Flt-3/Flk-2/CD135 Antibody (7E8.2C8) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC
Clone
7E8.2C8
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 500 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-42210AF350
Alexa Fluor 405
NBP2-42210AF405
Alexa Fluor 488
NBP2-42210AF488
Alexa Fluor 532
NBP2-42210AF532
Alexa Fluor 594
NBP2-42210AF594
Alexa Fluor 647
NBP2-42210AF647
Alexa Fluor 700
NBP2-42210AF700
Alexa Fluor 750
NBP2-42210AF750
Allophycocyanin
NBP2-42210APC
Biotin
NBP2-42210B
CoraFluor 1
NBP2-42210CL1
DyLight 350
NBP2-42210UV
DyLight 405
NBP2-42210V
DyLight 488
NBP2-42210G
DyLight 550
NBP2-42210R
DyLight 594
NBP2-42210DL594
DyLight 650
NBP2-42210C
DyLight 680
NBP2-42210FR
DyLight 755
NBP2-42210IR
FITC
NBP2-42210F
HRP
NBP2-42210H
Janelia Fluor 525
NBP2-42210JF525
Janelia Fluor 549
NBP2-42210JF549
Janelia Fluor 646
NBP2-42210JF646
Janelia Fluor 669
NBP2-42210JF669
PE
NBP2-42210PE
PerCP
NBP2-42210PCP
Unconjugated
NBP2-42210
mFluor Violet 450 SE
NBP2-42210MFV450
mFluor Violet 610 SE
NBP2-42210MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-42210
BSA Free
NBP2-42210SS
BSA Free
NBP2-42210
Azide and BSA Free
NBP2-80739
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Flt-3/Flk-2/CD135 Antibody (7E8.2C8) [mFluor Violet 500 SE] Summary

Immunogen
Partial recombinant human FLT3 protein (between amino acids 250-500) [UniProt P36888]
Isotype
IgG2b Lambda
Clonality
Monoclonal
Host
Mouse
Gene
FLT3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: ~86% to Mouse and Rat's FLT3 protein.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Flt-3/Flk-2/CD135 Antibody (7E8.2C8) [mFluor Violet 500 SE]

  • CD135 antigen
  • CD135
  • EC 2.7.10
  • fetal liver kinase 2
  • FL cytokine receptor
  • FLK2
  • Flk-2
  • FLT3 receptor tyrosine kinase
  • Flt3
  • Flt-3
  • Fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • growth factor receptor tyrosine kinase type III
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1EC 2.7.10.1
  • Tyrosine-protein kinase receptor FLT3

Background

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT3