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FIZZ1/RELM alpha Antibody (226033) [Unconjugated]

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FIZZ1/RELMa was detected in immersion fixed BV-2 mouse microglia cell line using Rat Anti-Mouse FIZZ1/RELMa Monoclonal Antibody (Catalog # MAB1523) at 25 µg/mL for 3 hours at room temperature. Cells were stained using ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ICC/IF
Clone
226033
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

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FIZZ1/RELM alpha Antibody (226033) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant mouse FIZZ1/RELM alpha
Asp24-Ser111
Accession # Q9EP95
Specificity
Detects mouse FIZZ1/RELM alpha in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) RELM beta or rmResistin is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
RETNLA
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 8-25 ug/mL
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB1523 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FIZZ1/RELM alpha Antibody (226033) [Unconjugated]

  • 1810019L16Rik
  • FIZZ1
  • Fizz-1
  • HIMF
  • RELM alpha
  • RELMa
  • RELMalpha
  • RELM-alpha
  • Retnla resistin like alpha
  • RETNLA
  • RETNLB
  • Xcp2

Background

RELM alpha , also known as ‘found in inflammatory zone 1’ (FIZZ1) belongs to the RELM/FIZZ family of cysteine rich secretory proteins. RELM alpha is most abundantly expressed in white adipose tissue but not in preadipocytes or 3T3-L1 adipocytes. RELM alpha expression is also detected in mammary tissue, heart, lung, and tongue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FIZZ1/RELM alpha Antibody (MAB1523)(5)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: Flow Cytometry, Fluorescence Microscopy, IHC.


Filter By Application
Flow Cytometry
(2)
Fluorescence Microscopy
(1)
IHC
(1)
All Applications
Filter By Species
Mouse
(4)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB1523 Applications Species
AJ Eastman, J Xu, J Bermik, N Potchen, A den Dekker, LM Neal, G Zhao, A Malachowsk, M Schaller, S Kunkel, JJ Osterholze, I Kryczek, MA Olszewski Epigenetic stabilization of DC and DC precursor classical activation by TNFalpha contributes to protective T cell polarization Sci Adv, 2019-12-04;5(12):eaaw9051. 2019-12-04 [PMID: 31840058] (Fluorescence Microscopy, Mouse) Fluorescence Microscopy Mouse
KA Smith, S Löser, F Varyani, Y Harcus, HJ McSorley, AN McKenzie, RM Maizels Concerted IL-25R and IL-4R? signaling drive innate type 2 effector immunity for optimal helminth expulsion Elife, 2018-09-21;7(0):. 2018-09-21 [PMID: 30238872] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Gail Deutsch, Akshay Muralidhar, Ellen Le, Ivan A. Borbon, Robert P. Erickson Extensive macrophage accumulation in young and old Niemann–Pick C1 model mice involves the alternative, M2, activation pathway and inhibition of macrophage apoptosis Gene 3/10/2016 [PMID: 26707209]
Barron L, Smith A, El Kasmi K, Qualls J, Huang X, Cheever A, Borthwick L, Wilson M, Murray P, Wynn T Role of arginase 1 from myeloid cells in th2-dominated lung inflammation. PLoS ONE, 2013-04-24;8(4):e61961. 2013-04-24 [PMID: 23637937] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, Gelpi E, Halle A, Korte M, Latz E, Golenbock D NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature, 2012-12-19;493(7434):674-8. 2012-12-19 [PMID: 23254930] (IHC, Mouse) IHC Mouse

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Bioinformatics

Gene Symbol RETNLA
Uniprot