Ficolin-3 Antibody (FCN334) - BSA Free Summary
Immunogen |
Recombinant human H-ficolin |
Specificity |
Reacts specifically with H-ficolin. No cross-reaction has been observed with L- or M-ficolin. |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
FCN3 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:32000
- Immunoprecipitation
- Sandwich ELISA
|
Application Notes |
ELISA: NBP1-41283 reacts with recombinant H-ficolin coated directly onto the microtiter well. A sandwich ELISA for H-ficolin uses NBP1-41283 for both capture and detection. (1) |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
10mM Phosphate (pH 7.4) and 0.5M NaCl |
Preservative |
0.09% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Protein A or G purified |
Alternate Names for Ficolin-3 Antibody (FCN334) - BSA Free
Background
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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