Orthogonal Strategies: Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Analysis in human bone marrow and pancreas tissues using NBP1-84706 antibody. Corresponding Ficolin-1 RNA-seq data are ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Staining of human bone marrow, gastrointestinal, lymphoid tissues and pancreas using Anti-Ficolin-1 antibody NBP1-84706 (A) ...read more
Western Blot: Ficolin-1 Antibody [NBP1-84706] - Lane 1: Marker [kDa] 219, 112, 85, 49, 32, 25, 18 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human cell line A-431 Lane 5: Human liver tissue
Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells.
Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Staining of human small intestine shows strong cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: Ficolin-1 Antibody [NBP1-84706] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: LAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FCN1
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Ficolin-1 Antibody - BSA Free
Collagen/fibrinogen domain-containing protein 1
FCN1
Fcna
FCNM
FCNMficolin-A
ficolin (collagen/fibrinogen domain containing) 1
ficolin (collagen/fibrinogen domain-containing) 1
Ficolin1
Ficolin-1
Ficolin-A
ficolin-alpha
M-ficolin
Background
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway (1).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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