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FGFR3 Antibody (136334) [Phycoerythrin]

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K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human FGF R3 PE-conjugated Monoclonal Antibody (Catalog # FAB766P, filled histogram) or isotype control antibody (Catalog # IC002P, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
136334
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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FGFR3 Antibody (136334) [Phycoerythrin] Summary

Additional Information
Clone 136334 was used by HLDA to establish CD designation
Immunogen
Pool of NS0-derived recombinant human FGF R3 alpha (IIIb) and Sf21-derived FGF R3 alpha (IIIc)
Specificity
Detects the IIIb and IIIc isoforms of human FGF R3 in direct ELISAs and Western blots. Does not cross-react with any isoforms of recombinant mouse (rm) FGF R3, rmFGF R2, recombinant human (rh) FGF R1, rhFGF R2, or rhFGF R4.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FGFR3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB766P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FGFR3 Antibody (136334) [Phycoerythrin]

  • CD333
  • CEK
  • EC 2.7.10
  • FGF R3
  • FGFR3
  • fibroblast growth factor receptor 3
  • HSFGFR3EX
  • JTK4
  • JTK4thanatophoric dwarfism

Background

Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfate proteoglycans as co‑factors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF -1, -2, -4, -8b, -8e, -8f, -9, and -17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FGFR3 Antibody (FAB766P)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(4)
All Applications
Filter By Species
Human
(3)
Mouse
(1)
All Species
Showing Publications 1 - 5 of 5.
Publications using FAB766P Applications Species
Vera B. Kaiser, Lana Talmane, Yatendra Kumar, Fiona Semple, Marie MacLennan, David R. Deciphering Developmental Disorders Study et al. Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome Genome Research 11/1/2021 [PMID: 34417209]
B Min, M Yoo, H Kim, M Cho, DH Nam, Y Yoon Semi-Automated Cell Panning for Efficient Isolation of FGFR3-Targeting Antibody International Journal of Molecular Sciences, 2021-06-09;22(12):. 2021-06-09 [PMID: 34207911] (Flow Cytometry, Human) Flow Cytometry Human
C Mennan, J Garcia, S Roberts, C Hulme, K Wright A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells Stem Cell Res Ther, 2019-03-18;10(1):99. 2019-03-18 [PMID: 30885254] (Flow Cytometry, Human) Flow Cytometry Human
ER Smith, SJ Tan, SG Holt, TD Hewitson FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts Sci Rep, 2017-06-13;7(1):3345. 2017-06-13 [PMID: 28611350] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Chandesris MO, Soulier J, Labaume S, Crinquette A, Repellini L, Chemin K, Malphettes M, Fieschi C, Asli B, Uzunhan Y, Fermand JP, Bories JC, Arnulf B Detection and follow-up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma. Br. J. Haematol., 2007-02-01;136(4):609-14. 2007-02-01 [PMID: 17223917] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol FGFR3