FFAR2/GPR43 Antibody (1000624) [Alexa Fluor® 594] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant human FFAR2/GPR43 Met1-Glu330 Accession # O15552 |
Specificity |
Detects human FFAR2/GPR43 in direct ELISAs. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 0.25-1 ug/10^6 cells
|
Packaging, Storage & Formulations
Storage |
Protect from light. Do not freeze.- 12 months from date of receipt, 2 to 8 °C as supplied.
|
Buffer |
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
Notes
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for FFAR2/GPR43 Antibody (1000624) [Alexa Fluor® 594]
Background
Human Free fatty acid receptor 2 (FFA2, FFAR2, GPCR43 or
GPR43) is a 330 aminoacids G-protein coupled receptor encoded by the FFAR2
gene. G-protein-coupled receptors (GPCRs) are seven-trans-membrane (7TM)
receptors that mediate cellular responses to the majority of hormones and
neurotransmitters and are common targets for drug discovery. Human GPR43/FFA2
is present in a large variety of tissues, including adipose tissue,
inflammatory cells, and gastrointestinal (GI) tract and is activated by
short-chain fatty acids (SCFAs). Studies on knockout mice have identified Free
Fatty Acid Receptor 2 (FFAR2 or GPR43) as a critical gene in the prevention of
obesity, colitis, asthma and arthritis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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