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Fc gamma RIIA/CD32a Antibody (VIB9600) - Humanized

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
VIB9600
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28630AF350
Alexa Fluor 405
NBP3-28630AF405
Alexa Fluor 488
NBP3-28630AF488
Alexa Fluor 532
NBP3-28630AF532
Alexa Fluor 594
NBP3-28630AF594
Alexa Fluor 647
NBP3-28630AF647
Alexa Fluor 700
NBP3-28630AF700
Alexa Fluor 750
NBP3-28630AF750
Allophycocyanin
NBP3-28630APC
Biotin
NBP3-28630B
CoraFluor 1
NBP3-28630CL1
DyLight 350
NBP3-28630UV
DyLight 405
NBP3-28630V
DyLight 488
NBP3-28630G
DyLight 550
NBP3-28630R
DyLight 594
NBP3-28630DL594
DyLight 650
NBP3-28630C
DyLight 680
NBP3-28630FR
DyLight 755
NBP3-28630IR
FITC
NBP3-28630F
HRP
NBP3-28630H
Janelia Fluor 525
NBP3-28630JF525
Janelia Fluor 549
NBP3-28630JF549
Janelia Fluor 585
NBP3-28630JF585
Janelia Fluor 635
NBP3-28630JF635
Janelia Fluor 646
NBP3-28630JF646
Janelia Fluor 669
NBP3-28630JF669
PE
NBP3-28630PE
PerCP
NBP3-28630PCP
mFluor Violet 450 SE
NBP3-28630MFV450
mFluor Violet 500 SE
NBP3-28630MFV500
mFluor Violet 610 SE
NBP3-28630MFV610
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Fc gamma RIIA/CD32a Antibody (VIB9600) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
FcgR2a / CD32a
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
FCGR2A
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Fc gamma RIIA/CD32a Antibody (VIB9600) - Humanized

  • CD32 antigen
  • CD32a
  • CD32MGC23887
  • CDw32fc-gamma-RIIa
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc gamma RIIA
  • FCG2
  • Fc-gamma RII-a
  • Fc-gamma-RIIa
  • FcGR
  • FCGR2
  • FCGR2A
  • FCGR2A1
  • FcgRIIA
  • FCRIIA
  • fcRII-a
  • IGFR2MGC30032
  • IgG Fc receptor II-a
  • Immunoglobulin G Fc receptor II
  • low affinity immunoglobulin gamma Fc region receptor II-a

Background

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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RIIA/CD32a Antibody ( ...
NBP3-28630
Fc gamma RIIA/CD32a Antibody (VIB9600) - Humanized
Species: Hu
Applications: ELISA, Flow, Func

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FAQs for Fc gamma RIIA/CD32a Antibody (NBP3-28630). (Showing 1 - 1 of 1 FAQ).

  1. Does any of your FCGR2A antibodies (19C10, 6D11, 13G9) cross react to FCGR2B?
    • For these antibodies, we have used the full-length protein FCGR2A (NP_067674) as the immunogen and we have not mapped the epitope that is detected with each Ab yet. I did an alignment of these two proteins and they are highly conserved thus it seems likely that there will be cross-reactivity.

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Bioinformatics

Gene Symbol FCGR2A
Uniprot