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Fc gamma RIIA/CD32a Antibody Pair [HRP]

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Sandwich ELISA: Fc gamma RIIA/CD32a Antibody Pair [HRP] [NBP2-79663] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Sandwich ELISA: Fc gamma RIIA/CD32a Antibody Pair [HRP] [NBP2-79663] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity RMSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
7.81-500 pg/ml (example only; lot dependent)
Sensitivity
7.8 pg/ml (example only; lot dependent)

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
HRP
NBP2-79663-5Plates
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Fc gamma RIIA/CD32a Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Rhesus Macaque Fc gamma RIIA/CD32a.
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Rhesus Macaque Fc gamma RIIA/CD32a.
Standard Curve Range
7.81-500 pg/ml (example only; lot dependent)
Sensitivity
7.8 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
FCGR2A

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Mouse Monoclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for Fc gamma RIIA/CD32a Antibody Pair [HRP]

  • CD32 antigen
  • CD32a
  • CD32MGC23887
  • CDw32fc-gamma-RIIa
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc gamma RIIA
  • FCG2
  • Fc-gamma RII-a
  • Fc-gamma-RIIa
  • FcGR
  • FCGR2
  • FCGR2A
  • FCGR2A1
  • FcgRIIA
  • FCRIIA
  • fcRII-a
  • IGFR2MGC30032
  • IgG Fc receptor II-a
  • Immunoglobulin G Fc receptor II
  • low affinity immunoglobulin gamma Fc region receptor II-a

Background

The FCGR2A gene encodes a low affinity immunoglobulin gamma Fc region receptor II-a protein that in isoform 1 is 317 amino acids long at 35 kDA and at isoform 2 is 316 amino acids long at nearly 35 kDA. These proteins are found on the surface of many immune system response cells that act as a low affinity receptor through encouraging responses against pathogens and soluble antigens. Additionally, it functions to initiate phagocytosis of opsonized antigens. FCGR2A participates in Fc-GammaR pathway, osteoclast differentiation, signaling events controlled by PTP1B, and NFAT in immune response. It is known to interact with genes SYK, FYN, HCK, LGALS3, and PIK3R1. FCGR2A is linked to lupus, thrombocytopenia, b-cell lymphomas, otitis media, adult-onset still's disease, guillain-barre syndrome, asymptomatic dengue, severe acute respiratory syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Product General Protocols

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FAQs for Fc gamma RIIA/CD32a Antibody Pair (NBP2-79663). (Showing 1 - 1 of 1 FAQ).

  1. Does any of your FCGR2A antibodies (19C10, 6D11, 13G9) cross react to FCGR2B?
    • For these antibodies, we have used the full-length protein FCGR2A (NP_067674) as the immunogen and we have not mapped the epitope that is detected with each Ab yet. I did an alignment of these two proteins and they are highly conserved thus it seems likely that there will be cross-reactivity.

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Contact Information

Product PDFs

  SDS
  Manual - Fc gamma RIIA/CD32a Antibody Pair [HRP]
  PDF Datasheet
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Bioinformatics

Gene Symbol FCGR2A