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Fc gamma RII/CD32 Antibody (SR1608)

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Western Blot: Fc gamma RII/CD32 Antibody (SR1608) [NBP3-22565] - Western blot analysis using NBP3-22565 in U937 cell lysate.
Western Blot: Fc gamma RII/CD32 Antibody (SR1608) [NBP3-22565] - Western blot analysis using NBP3-22565 in U937 cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
SR1608
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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Fc gamma RII/CD32 Antibody (SR1608) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human Fc gamma RII/CD32 (Uniprot #: P12318, P31994, P31995)
Specificity
Detects endogenous levels of total Fc gamma RII/CD32
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
FCGR2B
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Fc gamma RII/CD32 Antibody (SR1608)

  • CD32 antigen
  • CD32B
  • CD32Fc fragment of IgG, low affinity II, receptor for (CD32)
  • CDw32
  • Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • Fc fragment of IgG, low affinity IIb, receptor for (CD32)
  • Fc gamma RII
  • Fc gamma RIIb
  • FCG2
  • Fc-gamma RII-b
  • FcgammaRIIb
  • fc-gamma-RIIb
  • FCGR2
  • FcgRII
  • FcgRIIB
  • fcRII-b
  • FcRII-c
  • IGFR2
  • IgG Fc receptor II-b
  • low affinity immunoglobulin gamma Fc region receptor II-b

Background

CD32 is a receptor for the Fc region of complexed or aggregated immunoglobulins gamma. This is a low affinity receptor. It is Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in downmodulation of previous state of cell activation triggered via antigen receptors on B cells (BCR), T cells (TCR) or via another Fc receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FCGR2B