ETV6/Tel Antibody

Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N terminal pointed (PNT) domain that is involved in the protein protein interactions with itself and other proteins, and a C terminal DNA binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ELISA, FLOW, IF/IHC, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-80695	Applications	Species
Villar J, Cros A, De Juan A et al. ETV3 and ETV6 enable monocyte differentiation into dendritic cells by repressing macrophage fate commitment Nature immunology 2023-01-01 [PMID: 36543959] (WB, FLOW, Human)	WB, FLOW	Human
Romero Nunez E, Blanco Ayala T, Vazquez Cervantes GI et al. Pregestational Exposure to T. gondii Produces Maternal Antibodies That Recognize Fetal Brain Mimotopes and Induces Neurochemical and Behavioral Dysfunction in the Offspring Cells 2022-11-29 [PMID: 36497079] (ELISA, Rat)	ELISA	Rat
Li T, Li L, Peng R et al. Abrocitinib Attenuates Microglia-Mediated Neuroinflammation after Traumatic Brain Injury via Inhibiting the JAK1/STAT1/NF-kappa B Pathway Cells 2022-11-13 [PMID: 36429017] (WB, Mouse)	WB	Mouse
Leila Noetzli, Richard W Lo, Alisa B Lee-Sherick et al. Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. Nature Genetics 2015-03-25 [PMID: 25807284] (IF/IHC, Human)	IF/IHC	Human
Ek S, Andreasson U, Hober S et al. From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. Mol Cell Proteomics 2006-06-01 [PMID: 16524965]

Array NBP1-80695

• ETV6/Tel Antibodies
• ETV6/Tel Lysate
• ETV6/Tel Protein