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ESAM Antibody (408519) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
408519
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4204U-100UG
Alexa Fluor 405
FAB4204V-100UG
Alexa Fluor 488
FAB4204G-100UG
Alexa Fluor 532
FAB4204X
Alexa Fluor 594
FAB4204T-100UG
Alexa Fluor 647
FAB4204R-100UG
Alexa Fluor 700
FAB4204N-100UG
Alexa Fluor 750
FAB4204S-100UG
Allophycocyanin
FAB4204A
Allophycocyanin/Cy7
FAB4204APCCY7
Biotin
FAB4204B
CoraFluor 1
FAB4204CL1
DyLight 350
FAB4204D
DyLight 405
FAB4204E
DyLight 488
FAB4204K
DyLight 550
FAB4204L
DyLight 594
FAB4204M
DyLight 650
FAB4204W
DyLight 680
FAB4204Y
DyLight 755
FAB4204Z
HRP
FAB4204H
Janelia Fluor 525
FAB4204JF525
Janelia Fluor 646
FAB4204J
Janelia Fluor 669
FAB4204JF669
PE/Atto594
FAB4204PEATT594
PE/Cy5.5
FAB4204PECY55
PE/Cy7
FAB4204PECY7
PerCP
FAB4204C
Unconjugated
MAB4204
mFluor Violet 450 SE
FAB4204MFV450
mFluor Violet 500 SE
FAB4204MFV500
mFluor Violet 610 SE
FAB4204MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB4204
Carrier Free
MAB4204
Carrier Free
FAB4204A
Carrier Free
MAB4204-SP
Carrier Free
FAB4204V-100UG
Carrier Free
FAB4204U-100UG
Carrier Free
FAB4204T-100UG
Carrier Free
FAB4204S-100UG
Carrier Free
FAB4204R-100UG
Carrier Free
FAB4204N-100UG
Carrier Free
FAB4204G-100UG
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ESAM Antibody (408519) [Janelia Fluor® 549] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ESAM
Gln30-Ala247
Accession # Q96AP7
Specificity
Detects human ESAM in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse ESAM is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ESAM
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ESAM Antibody (408519) [Janelia Fluor® 549]

  • 2310008D05Rik
  • endothelial cell adhesion molecule
  • endothelial cell-selective adhesion molecule
  • ESAM
  • HUEL (C4orf1)-interacting protein
  • LP4791 protein
  • W117m

Background

ESAM is a tight junction regulatory protein involved in cell adhesion and is expressed only on endothelial cells and activated platelets. It may mediate aggregation through a homophilic molecular interaction (By similarity). ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel walls and it may have a role in signaling mechanisms that trigger the opening of endothelial cell contacts. A correlation has been found between ESAM expression and lymph node metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ESAM