EPCR Antibody [Biotin]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Protein C is a vitamin K-dependent serine protease that plays a major role in blood coagulation. Binding of Protein C to EPCR leads to the proteolytic activation of PAR1 (protease-activated receptor 1) on endothelial cells and subsequent up-regulation of Protein C-induced genes. EPCR is a type I transmembrane glycoprotein in the CD1/MHC family. It is expressed most strongly in the endothelial cells of arteries and veins in heart and lung. Membrane bound EPCR is released by metalloproteolytic cleavage to generate the soluble receptor. The extracellular domain of human and mouse EPCR shares approximately 61% amino acid sequence homology.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: ELISA Detection, ELISA Development.

Showing Publications 1 - 2 of 2.

Publications using BAF2245	Applications	Species
D Wang, X Hu, C Liu, Y Jia, Y Bai, C Cai, J Wang, L Bai, R Yang, C Lin, YR Liu, S Li, F Qiao, L Yao, L Chen, G Ge, H Jiang, D Li, L Li, J Chen, ZM Shao, YA Zeng Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers Cell Res., 2019-09-03;0(0):. 2019-09-03 [PMID: 31481760] (ELISA Detection, Human)	ELISA Detection	Human
Gunawardana CG, Kuk C, Smith CR Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. J. Proteome Res., 2009-10-01;8(10):4705-13. 2009-10-01 [PMID: 19663500] (ELISA Development, Human)	ELISA Development	Human

Array BAF2245

• EPCR Antibodies
• EPCR Lysate
• EPCR Proteins
• EPCR Proteins and Enzymes
• EPCR ELISA