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Endothelin-3 Antibody

Images

 
Western Blot: Endothelin-3 Antibody [H00001908-D01P] - Analysis of EDN3 expression in human placenta.
Western Blot: Endothelin-3 Antibody [H00001908-D01P] - Analysis of EDN3 expression in transfected 293T cell line by EDN3 polyclonal antibody.Lane 1: EDN3 transfected lysate(25.50 KDa).Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Endothelin-3 Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
EDN3 (NP_000105.1, 1 a.a. - 238 a.a.) full-length human protein. MEPGLWLLFGLTVTSAAGFVPCSQSGDAGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
Specificity
EDN3 - endothelin 3,
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EDN3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Endothelin-3 Antibody

  • EDN3
  • endothelin 3
  • Endothelin3
  • Endothelin-3
  • ET3
  • ET-3
  • HSCR4
  • MGC15067
  • MGC61498
  • PPET3
  • preproendothelin-3
  • truncated endothelin 3
  • WS4B

Background

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol EDN3
Entrez
Uniprot