EML4 Antibody

Echinoderm microtubule associated protein like 4 (EML4) has been identified as part of a gene fusion with the kinase domain of the anaplastic lymphoma receptor tyrosine kinase (ALK) in non-small cell lung cancer. EML4 associates with in vitro polymerized microtubules. In the cell, phosphorylated EML4 associates with the mitotic spindle and is essential for proliferation and microtubule network formation. Alternative names for EML4 include EMAPL4, ropp120, C2orf2, ELP120, and EMAP-4.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IF/IHC, IHC-P, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-86805	Applications	Species
Madgwick A, Fort P, Hanson PS et al. Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program. PLoS One 2015-01-01 [PMID: 25993117] (WB, Human)	WB	Human
Schoppmann SF, Streubel B, Birner P. Amplification but not translocation of anaplastic lymphoma kinase is a frequent event in oesophageal cancer Eur J Cancer 2013-03-11 [PMID: 23490651] (IF/IHC, Human)	IF/IHC	Human
Preusser M, Berghoff AS, Ilhan-Mutlu A et al. ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer. Lung Cancer 2013-02-27 [PMID: 23453647] (IHC-P, Human)	IHC-P	Human

Array NBP1-86805

• EML4 Antibodies
• EML4 Lysate
• EML4 Proteins