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E-Cadherin Antibody (114420) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready, ICC/IF
Clone
114420
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7481U-100UG
Alexa Fluor 405
FAB7481V-100UG
Alexa Fluor 488
FAB7481G-100UG
Alexa Fluor 532
FAB7481X
Alexa Fluor 594
FAB7481T-100UG
Alexa Fluor 647
FAB7481R-100UG
Alexa Fluor 700
FAB7481N-100UG
Alexa Fluor 750
FAB7481S-100UG
Allophycocyanin
FAB7481A-100
Allophycocyanin
FAB7481A-025
Allophycocyanin/Cy7
FAB7481APCCY7
Biotin
FAB7481B
CoraFluor 1
FAB7481CL1
DyLight 350
FAB7481D
DyLight 405
FAB7481E
DyLight 488
FAB7481K
DyLight 550
FAB7481L
DyLight 594
FAB7481M
DyLight 650
FAB7481W
DyLight 680
FAB7481Y
DyLight 755
FAB7481Z
HRP
FAB7481H
Janelia Fluor 525
FAB7481JF525
Janelia Fluor 585
FAB7481JF585
Janelia Fluor 635
FAB7481JF635
Janelia Fluor 646
FAB7481J
Janelia Fluor 669
FAB7481JF669
PE/Atto594
FAB7481PEATT594
PE/Cy5.5
FAB7481PECY55
PE/Cy7
FAB7481PECY7
PerCP
FAB7481C
Phycoerythrin
FAB7481P-025
Phycoerythrin
FAB7481P-100
Unconjugated
MAB7481
mFluor Violet 450 SE
FAB7481MFV450
mFluor Violet 500 SE
FAB7481MFV500
mFluor Violet 610 SE
FAB7481MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7481
Carrier Free
MAB7481
Carrier Free
MAB7481-SP
Carrier Free
FAB7481P-100
Carrier Free
FAB7481P-025
Carrier Free
FAB7481A-100
Carrier Free
FAB7481A-025
Carrier Free
FAB7481V-100UG
Carrier Free
FAB7481U-100UG
Carrier Free
FAB7481T-100UG
Carrier Free
FAB7481S-100UG
Carrier Free
FAB7481R-100UG
Carrier Free
FAB7481N-100UG
Carrier Free
FAB7481G-100UG
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E-Cadherin Antibody (114420) [Janelia Fluor® 549] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse E-Cadherin
Asp157-Val709 (predicted)
Accession # P09803
Specificity
Detects mouse E-Cadherin in direct ELISAs and Western blots.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CDH1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for E-Cadherin Antibody (114420) [Janelia Fluor® 549]

  • Arc-1
  • CAD1
  • cadherin 1, E-cadherin (epithelial)
  • cadherin 1, type 1, E-cadherin (epithelial)
  • Cadherin-1
  • calcium-dependent adhesion protein, epithelial
  • CAM 120/80
  • CD324 antigen
  • CD324
  • CDH1
  • CDHE
  • cell-CAM 120/80
  • Cell-CAM120/80
  • ECAD
  • ECadherin
  • E-Cadherin
  • Epithelial cadherin
  • LCAM
  • L-CAM
  • UVOE-Cadherin
  • Uvomorulin

Background

E-cadherin, or epithelial cadherin, is an cell-cell adhesion glycoprotein important to cellular processes such as morphology, polarity, development, tissue integrity and migration. E cadherin's extracellular domain interacts with other E-cadherin protein on adjacent epithelial cells to establish adhesion between them. E cadherin has also been identified as a tumor and metastasis suppressor, and its mutations have been linked to various forms of cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDH1