DPPA4 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

DPPA4 is a 33 kDa molecule that is expressed specifically in the early embryo, uncommitted cells of the germ line, and embryonic stem cells and is used as a marker of pluripotent cells. Mouse DPPA4 is 296 amino acids in length and contains an SAP (SAF-A/B, ACINUS, PIAS) putative DNA-binding domain. Two potential isoforms exist with deletions of amino acids 104‑120 and 69‑120, respectively. In the region used as an immunogen, mouse DPPA4 shows 57% amino acid sequence identity with human and 87% identity with rat DPPA4 proteins.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 4 applications: ChIP, ICC, IHC, Western Blot.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using AF3730	Applications	Species
Simon Suppinger, Marietta Zinner, Nadim Aizarani, Ilya Lukonin, Raphael Ortiz, Chiara Azzi et al. Multimodal characterization of murine gastruloid development Cell Stem Cell 6/1/2023 [PMID: 37209681]
O'Shea TM, Ao Y, Wang S et al. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice Nature Communications 9/28/2022 [PMID: 36171203]
O'Shea TM, Ao Y, Wang S et al. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice Nature Communications 2022-09-28 [PMID: 36171203]
Oana Kubinyecz, Fatima Santos, Deborah Drage, Wolf Reik, Melanie A. Eckersley-Maslin Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival Development 12/15/2021 [PMID: 34931676]
I Theurillat, IA Hendriks, JC Cossec, A Andrieux, ML Nielsen, A Dejean Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells Cell Rep, 2020-09-15;32(11):108146. 2020-09-15 [PMID: 32937131] (Western Blot, Mouse)	Western Blot	Mouse
L Vanheer, J Song, N De Geest, A Janiszewsk, I Talon, C Provenzano, T Oh, J Chappell, V Pasque Tox4 modulates cell fate reprogramming J. Cell. Sci., 2019-10-22;0(0):. 2019-10-22 [PMID: 31519808] (ICC, Mouse)	ICC	Mouse
JM Stringer, SC Forster, Z Qu, L Prokopuk, MK O'Bryan, DK Gardner, SJ White, D Adelson, PS Western Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance BMC Biol., 2018-09-20;16(1):104. 2018-09-20 [PMID: 30236109] (IHC, Mouse)	IHC	Mouse
RH Klein, PY Tung, P Somanath, HJ Fehling, PS Knoepfler Genomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer Stem Cell Res, 2018-07-19;31(0):83-94. 2018-07-19 [PMID: 30031967] (ChIP, Mouse)	ChIP	Mouse
K Adachi, W Kopp, G Wu, S Heising, B Greber, M Stehling, MJ Araúzo-Bra, ST Boerno, B Timmermann, M Vingron, HR Schöler Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency Cell Stem Cell, 2018-06-14;0(0):. 2018-06-14 [PMID: 29910149] (IHC, Mouse)	IHC	Mouse
M Sone, N Morone, T Nakamura, A Tanaka, K Okita, K Woltjen, M Nakagawa, JE Heuser, Y Yamada, S Yamanaka, T Yamamoto Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency Cell Metab., 2017-05-02;25(5):1103-1117.e6. 2017-05-02 [PMID: 28467928] (ICC, Mouse)	ICC	Mouse
Tung P, Varlakhanova N, Knoepfler P Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes. Stem Cells, 2013-11-01;31(11):2330-42. 2013-11-01 [PMID: 23963736] (ChIP, Mouse)	ChIP	Mouse
Denise C. Miles, Stephanie I. Wakeling, Jessica M. Stringer, Jocelyn A. van den Bergen, Dagmar Wilhelm, Andrew H. Sinclair et al. Signaling through the TGF Beta-Activin Receptors ALK4/5/7 Regulates Testis Formation and Male Germ Cell Development PLoS ONE 1/16/2013 [PMID: 23342175]
Patrick S. Western, Rachael A. Ralli, Stephanie I. Wakeling, Camden Lo, Jocelyn A. van den Bergen, Denise C. Miles et al. Mitotic Arrest in Teratoma Susceptible Fetal Male Germ Cells PLoS ONE 6/2/2011 [PMID: 21674058]
Show All 13 Publications. Collapse Publications.

Array AF3730

• DPPA4 Antibodies
• DPPA4 Lysate
• DPPA4 Proteins