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Dopamine D5R/DRD5 Antibody

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Western Blot: Dopamine D5R/DRD5 Antibody [NBP3-10782] - Western blot analysis of Dopamine D5R/DRD5 in Human 293T Whole Cell. Antibody dilution at 1.0ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Dopamine D5R/DRD5 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human Dopamine D5R/DRD5 (NP_000789.1). Peptide sequence IVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDP
Clonality
Polyclonal
Host
Rabbit
Gene
DRD5
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Dopamine D5R/DRD5 Antibody

  • D(1B) dopamine receptor
  • D(5) dopamine receptor
  • D1beta dopamine receptor
  • DBDR
  • Dopamine D5 R
  • Dopamine D5 receptor
  • Dopamine D5R
  • dopamine receptor D1B
  • dopamine receptor D5
  • DRD1B
  • DRD1BDBDR
  • DRD1L2
  • DRD1L2MGC10601
  • DRD5

Background

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DRD5